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Q49721 (Y388_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uncharacterized oxidoreductase ML0388
EC=1.-.-.-
Gene names
Ordered Locus Names:ML0388
ORF Names:B1620_C2_193
OrganismMycobacterium leprae [Complete proteome] [HAMAP]
Taxonomic identifier1769 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the IMPDH/GMPR family.

Sequence caution

The sequence CAC29896.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionoxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 375375Uncharacterized oxidoreductase ML0388
PRO_0000093784

Regions

Compositional bias241 – 2488Ala-rich

Sequences

Sequence LengthMass (Da)Tools
Q49721 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: CE22C3E84E1CA018

FASTA37538,924
        10         20         30         40         50         60 
MVEIGMGRVA RRTYELREIS IVPSRRTRSS KDVSTAWQLD AYRFEIPVVA HPTDALVSPE 

        70         80         90        100        110        120 
FAIELGRLGG LGVLNGEGLI GRHADVGAKV AQLIEAAEKE PEPATAVCLL QELHAAPLNP 

       130        140        150        160        170        180 
DLLGSAVARI REAGVTTAVR VSPQNAQVLT PVLLAAGIDL LVVQGSIVSA ECVASGGEPL 

       190        200        210        220        230        240 
NLKTFISELD VPVVAGGVLD HRTALHLMRT GAAGVIVGYG STRGATTSDE VLGISVPMAT 

       250        260        270        280        290        300 
AIADAAAARR EYLDETGGRY VHVLADGDIY TSGELAKAIA CGADAVVLGT PLAQSAEALG 

       310        320        330        340        350        360 
GGWFWPAAAA HPSLPRGALL QTAVGERPSL QQVLNGPSDN PFGTLNLVGG LRRSMAKAGY 

       370 
CDLKEFQKVG LIVSI

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00015 Genomic DNA. Translation: AAC43221.1.
AL583918 Genomic DNA. Translation: CAC29896.1. Different initiation.
PIRD86957.
S72812.
RefSeqNP_301378.1. NC_002677.1.

3D structure databases

ProteinModelPortalQ49721.
SMRQ49721. Positions 2-374.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000028527; EBMYCP00000028133; EBMYCG00000028522.
GeneID909090.
GenomeReviewsGene locus ML0388 in contig AL450380_GR.
KEGGmle:ML0388.
NMPDRfig|272631.1.peg.250.
PATRIC18051410. VBIMycLep78757_0654.

Organism-specific databases

LepromaML0388.
CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017422.
HOGENOMHBG284613.
ProtClustDBPRK08649.

Enzyme and pathway databases

BioCycMLEP272631:ML0388-MONOMER.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR005992. IMP_DH-rel2.
IPR001093. IMP_DH_GMPRt.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00088.
PANTHERPTHR11911:SF29. PTHR11911:SF29. 1 hit.
PfamPF00478. IMPDH. 1 hit.
[Graphical view]
TIGRFAMsTIGR01304. IMP_DH_rel_2. 1 hit.
ProtoNetSearch...

Entry information

Entry nameY388_MYCLE
AccessionPrimary (citable) accession number: Q49721
Secondary accession number(s): Q9CCV2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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