Unreviewed, UniProtKB/TrEMBL Q495R6 (Q495R6_HUMAN)

Names and origin

Protein names

Submitted name:
    MCM8 protein EMBL AAI01056.1

Gene names

Name:

MCM8 EMBL AAI01056.1

Organism

Homo sapiens (Human) EMBL AAI01056.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	880 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the MCM family. RuleBase RU004070V3 Contains 1 MCM domain. Spearmint SPM001208

Ontologies

Keywords
Ligand	ATP-binding Spearmint SPM001208 DNA-binding Spearmint SPM001208 Nucleotide-binding
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q495R6-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: C14BC2A3273EE6C6	FASTA	880	97,904
	10 20 30 40 50 60 MNGEYRGRGF GRGRFQSWKR GRGGGNFSGK WREREHRPDL SKTTGKRTSE QTPQFLLSTK 70 80 90 100 110 120 TPQSMQSTLD RFIPYKGWKL YFSEVYSDSS PLIEKIQAFE KFFTRHIDLY DKDEIERKGS 130 140 150 160 170 180 ILVDFKELTE GGEVTNLIPD IATELRDAPE KTLACMGLAI HQVLTKDLER HAAELQAQEG 190 200 210 220 230 240 LSNDGETMVN VPHIHARVYN YEPLTQLKNV RANYYGKYIA LRGTVVRVSN IKPLCTKMAF 250 260 270 280 290 300 LCAACGEIQS FPLPDGKYSL PTKCPVPVCR GRSFTALRSS PLTVTMDWQS IKIQELMSDD 310 320 330 340 350 360 QREAGRIPRT IECELVHDLV DSCVPGDTVT ITGIVKVSNA EEGSRNKNDK CMFLLYIEAN 370 380 390 400 410 420 SISNSKGQKT KSSEDGCKHG MLMEFSLKDL YAIQEIQAEE NLFKLIVKWS LALSPRLEYS 430 440 450 460 470 480 GAISAHCNLH LPSSNSSPTS ACRVAGTTGM RHQTQLLLLV KAGLALALFG GSQKYADDKN 490 500 510 520 530 540 RIPIRGDPHI LVVGDPGLGK SQMLQAACNV APRGVYVCGN TTTTSGLTVT LSKDSSSGDF 550 560 570 580 590 600 ALEAGALVLG DQGICGIDEF DKMGNQHQAL LEAMEQQSIS LAKAGVVCSL PARTSIIAAA 610 620 630 640 650 660 NPVGGHYNKA KTVSENLKMG SALLSRFDLA FILLDTPNEH HDHLLSEHVI AIRAGKQRTI 670 680 690 700 710 720 SSATVARMNS QDSNTSVLEV VSEKPLSERL KVVPGETIDP IPHQLLRKYI GYARQYVYPR 730 740 750 760 770 780 LSTEAARVLQ DFYLELRKQS QRLNSSPITT RQLESLIRLT EARARLELRE EATKEDAEDI 790 800 810 820 830 840 VEIMKYSMLG TYSDEFGNLD FERSQHGSGM SNRSTAKRFI SALNNVAERT YNNIFQFHQL 850 860 870 880 RQIAKELNIQ VADFENFIGS LNDQGYLLKK GPKVYQLQTM

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI01056.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC101055 mRNA. Translation: AAI01056.1.
UniGene	Hs.631506
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000125885. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:16147. MCM8.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	Q495R6.
HOVERGEN	Q495R6.
Gene expression databases
ArrayExpress	Q495R6.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase_core. IPR001208. DNA-dep_ATPase_MCM. IPR012340. NA-bd_OB-fold. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
Pfam	PF00493. MCM. 1 hit. [Graphical view]
PRINTS	PR01657. MCMFAMILY.
ProDom	PD001041. MCM. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00382. AAA. 1 hit. SM00350. MCM. 1 hit. [Graphical view]
PROSITE	PS50051. MCM_2. 1 hit. [Graphical view]

Entry information

Entry name

Q495R6_HUMAN

Accession

Primary (citable) accession number: Q495R6

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	November 25, 2008
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)