ID   Q494Q0_ARATH            Unreviewed;       409 AA.
AC   Q494Q0; A0A178VDP7;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 124.
DE   SubName: Full=At3g06170 {ECO:0000313|EMBL:AAZ23918.1};
DE   SubName: Full=Serinc-domain containing serine and sphingolipid biosynthesis protein {ECO:0000313|EMBL:AEE74356.1};
GN   OrderedLocusNames=At3g06170 {ECO:0000313|EMBL:AEE74356.1};
GN   ORFNames=F28L1.11 {ECO:0000313|EMBL:AEE74356.1}, F28L1_11
GN   {ECO:0000313|EMBL:AEE74356.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:AAZ23918.1};
RN   [1] {ECO:0000313|EMBL:AEE74356.1, ECO:0000313|Proteomes:UP000006548}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX   PubMed=11130713; DOI=10.1038/35048706;
RG   European Union Chromosome 3 Arabidopsis Sequencing Consortium;
RG   Institute for Genomic Research;
RG   Kazusa DNA Research Institute;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Blocker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M.,
RA   Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N.,
RA   Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L.,
RA   Weissenbach J., Saurin W., Quetier F., Schafer M., Muller-Auer S.,
RA   Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N.,
RA   Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P.,
RA   Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S.,
RA   Simionati B., Conrad A., Hornischer K., Kauer G., Lohnert T.H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schon O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwalder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.W., Mayer K.F., Kaul S.,
RA   Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2] {ECO:0000313|EMBL:AAZ23918.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Cheuk R., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AEE74356.1}
RP   NUCLEOTIDE SEQUENCE.
RG   TAIR;
RA   Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AEE74356.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA   Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|Proteomes:UP000006548}
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TDE1 family.
CC       {ECO:0000256|ARBA:ARBA00006665}.
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DR   EMBL; BT023726; AAZ23918.1; -; mRNA.
DR   EMBL; CP002686; AEE74356.1; -; Genomic_DNA.
DR   RefSeq; NP_187268.2; NM_111492.5.
DR   AlphaFoldDB; Q494Q0; -.
DR   SMR; Q494Q0; -.
DR   IntAct; Q494Q0; 16.
DR   STRING; 3702.Q494Q0; -.
DR   PaxDb; 3702-AT3G06170-1; -.
DR   ProteomicsDB; 181482; -.
DR   EnsemblPlants; AT3G06170.1; AT3G06170.1; AT3G06170.
DR   GeneID; 819791; -.
DR   Gramene; AT3G06170.1; AT3G06170.1; AT3G06170.
DR   KEGG; ath:AT3G06170; -.
DR   TAIR; AT3G06170; -.
DR   eggNOG; KOG2592; Eukaryota.
DR   HOGENOM; CLU_029574_1_1_1; -.
DR   OMA; GNPRVWY; -.
DR   OrthoDB; 296357at2759; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q494Q0; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005016; TDE1/TMS.
DR   PANTHER; PTHR10383:SF60; OS03G0454100 PROTEIN; 1.
DR   PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR   Pfam; PF03348; Serinc; 1.
PE   1: Evidence at protein level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0007829|PeptideAtlas:Q494Q0,
KW   ECO:0007829|ProteomicsDB:Q494Q0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        209..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          301..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   409 AA;  44877 MW;  BC7623885E1BC6C0 CRC64;
     MACCLASCCA SATCGLCSSV ASGISRKSAR IAYCGLFGAS LVVSWILRET GAPLLEKLPW
     INTSDSYTKE WYQQQAVLRV SFGNFLFFAI YALIMIGVKD QNDRRDSWHH GGWGLKMIVW
     FLLVVLMFFV PNVIVSLYGT LSKFGAGAFL LVQVVLLLDA THNWNDSWVE KDEKKWYIAL
     LVISIVCYIA TYTFSGILFI WFNPSGQDCG LNVFFIVMPM ILAFVFAIIA LHPAVNGSLL
     PASVISVYCA YVCYTGLSSE PHDYVCNGLN KSKAVNASTL ILGMLTTVLS VLYSALRAGS
     STTFLSPPSS PRSGVKDALL GDPEDGKKSG EAEARPVSYS YSFFHIIFAL ASMYAAMLLS
     GWTDSSESAT LIDVGWTSVW VKICTGWVTA GLYIWTLIAP LILPDREFY
//