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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Blochmannia pennsylvanicus (strain BPEN)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Enzyme and pathway databases

BioCyciCBLO291272:G1G3Y-13-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:BPEN_013
OrganismiBlochmannia pennsylvanicus (strain BPEN)
Taxonomic identifieri291272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia
Proteomesi
  • UP000007794 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000213781 – 115Ribonuclease P protein componentAdd BLAST115

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi291272.BPEN_013

Structurei

3D structure databases

ProteinModelPortaliQ494B8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105NVJ Bacteria
COG0594 LUCA
HOGENOMiHOG000266301
KOiK03536
OMAiLHQHELP
OrthoDBiPOG091H011Y

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
IPR020539 RNase_P_CS
PANTHERiPTHR33992 PTHR33992, 1 hit
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR00188 rnpA, 1 hit
PROSITEiView protein in PROSITE
PS00648 RIBONUCLEASE_P, 1 hit

Sequencei

Sequence statusi: Complete.

Q494B8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRKFLPKRA RLLNLNEFIF VFQKPERVKT TGITLFSRSN RLGYPRIGLA
60 70 80 90 100
ISKKYVKYAH ERNRIKRHIR ETFRTCQHNL LAKDFVLTIR SKEIIYYKNK
110
TLIQELEKLW YHHLC
Length:115
Mass (Da):14,051
Last modified:September 13, 2005 - v1
Checksum:i81009A78EDA6AF8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000016 Genomic DNA Translation: AAZ40663.1
RefSeqiWP_011282569.1, NC_007292.1

Genome annotation databases

EnsemblBacteriaiAAZ40663; AAZ40663; BPEN_013
KEGGibpn:BPEN_013

Similar proteinsi

Entry informationi

Entry nameiRNPA_BLOPB
AccessioniPrimary (citable) accession number: Q494B8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: April 25, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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