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Q49420

- CSD_MYCGE

UniProt

Q49420 - CSD_MYCGE

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Protein
Probable cysteine desulfurase
Gene
csd, MG336
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine By similarity.

Catalytic activityi

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactori

Pyridoxal phosphate By similarity.

GO - Molecular functioni

  1. cysteine desulfurase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-386-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine desulfurase (EC:2.8.1.7)
Gene namesi
Name:csd
Ordered Locus Names:MG336
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Probable cysteine desulfurase
PRO_0000150299Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei225 – 2251N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_336.

Structurei

3D structure databases

ProteinModelPortaliQ49420.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0520.
KOiK11717.
OMAiFRQAFPY.
OrthoDBiEOG68DD0M.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000192. Aminotrans_V/Cys_dSase.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49420-1 [UniParc]FASTAAdd to Basket

« Hide

MSAIKFNPSS FRKNFKWFEN NKNWINFDNA ATSIALDVVA EASKEYYQYF    50
CVNPHNKNPE INQKLIAIIE ETRDLLAKFF NAKKNEIIFT SSATESLNLF 100
AFGLSSLVKS NDEIILKEDE HAANVFPWVN LAKENKAKLK IIKKTPNKSW 150
TDAFLKACTP STKLLVITAT SNLFGNSIDY EKISKHLKKI SPNSFIVVDA 200
VQAVPHHKID ITSANIDFLT FSTHKFYGPT GLGIAFIKSE LQSRLKPFKL 250
GGDIFKSLDN NFKIIFKEGP SKFEAGTLNI MAIYALNKQL KFMQKEFNFS 300
EMVFYSKQLK NLAYQLLSQN PNIVLANHDQ DVPIFAFKHK YINSADLATF 350
LNIKKIIVRQ GSICVGKFKN KESFLRVSLL HYNTKEELLY LEKLLKTSKN 400
SIINELIY 408
Length:408
Mass (Da):46,618
Last modified:November 1, 1996 - v1
Checksum:iF16A009B463EBDAD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71561.1.
U02256 Genomic DNA. Translation: AAD12521.1.
PIRiB64237.
RefSeqiNP_073006.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71561; AAC71561; MG_336.
GeneIDi875461.
KEGGimge:MG_336.
PATRICi20010232. VBIMycGen98045_0393.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71561.1 .
U02256 Genomic DNA. Translation: AAD12521.1 .
PIRi B64237.
RefSeqi NP_073006.1. NC_000908.2.

3D structure databases

ProteinModelPortali Q49420.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_336.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71561 ; AAC71561 ; MG_336 .
GeneIDi 875461.
KEGGi mge:MG_336.
PATRICi 20010232. VBIMycGen98045_0393.

Phylogenomic databases

eggNOGi COG0520.
KOi K11717.
OMAi FRQAFPY.
OrthoDBi EOG68DD0M.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-386-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR000192. Aminotrans_V/Cys_dSase.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
Pfami PF00266. Aminotran_5. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
PROSITEi PS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 241-330.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiCSD_MYCGE
AccessioniPrimary (citable) accession number: Q49420
Secondary accession number(s): Q49361
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi