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Protein

Probable cysteine desulfurase

Gene

csd

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.By similarity

Catalytic activityi

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactori

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciMGEN243273:G1GJ2-420-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine desulfurase (EC:2.8.1.7)
Gene namesi
Name:csd
Ordered Locus Names:MG336
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000807 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001502991 – 408Probable cysteine desulfuraseAdd BLAST408

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei225N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PRIDEiQ49420

Structurei

3D structure databases

ProteinModelPortaliQ49420
SMRiQ49420
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK11717
OMAiNIECRYG
OrthoDBiPOG091H02CX

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR000192 Aminotrans_V_dom
IPR020578 Aminotrans_V_PyrdxlP_BS
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00266 Aminotran_5, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00595 AA_TRANSFER_CLASS_5, 1 hit

Sequencei

Sequence statusi: Complete.

Q49420-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAIKFNPSS FRKNFKWFEN NKNWINFDNA ATSIALDVVA EASKEYYQYF
60 70 80 90 100
CVNPHNKNPE INQKLIAIIE ETRDLLAKFF NAKKNEIIFT SSATESLNLF
110 120 130 140 150
AFGLSSLVKS NDEIILKEDE HAANVFPWVN LAKENKAKLK IIKKTPNKSW
160 170 180 190 200
TDAFLKACTP STKLLVITAT SNLFGNSIDY EKISKHLKKI SPNSFIVVDA
210 220 230 240 250
VQAVPHHKID ITSANIDFLT FSTHKFYGPT GLGIAFIKSE LQSRLKPFKL
260 270 280 290 300
GGDIFKSLDN NFKIIFKEGP SKFEAGTLNI MAIYALNKQL KFMQKEFNFS
310 320 330 340 350
EMVFYSKQLK NLAYQLLSQN PNIVLANHDQ DVPIFAFKHK YINSADLATF
360 370 380 390 400
LNIKKIIVRQ GSICVGKFKN KESFLRVSLL HYNTKEELLY LEKLLKTSKN

SIINELIY
Length:408
Mass (Da):46,618
Last modified:November 1, 1996 - v1
Checksum:iF16A009B463EBDAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA Translation: AAC71561.1
U02256 Genomic DNA Translation: AAD12521.1
PIRiB64237
RefSeqiWP_010869440.1, NC_000908.2

Genome annotation databases

EnsemblBacteriaiAAC71561; AAC71561; MG_336
KEGGimge:MG_336

Similar proteinsi

Entry informationi

Entry nameiCSD_MYCGE
AccessioniPrimary (citable) accession number: Q49420
Secondary accession number(s): Q49361
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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