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Q49420 (CSD_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cysteine desulfurase

EC=2.8.1.7
Gene names
Name:csd
Ordered Locus Names:MG336
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine By similarity.

Catalytic activity

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactor

Pyridoxal phosphate By similarity.

Sequence similarities

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functioncysteine desulfurase activity

Inferred from electronic annotation. Source: UniProtKB-EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408Probable cysteine desulfurase
PRO_0000150299

Amino acid modifications

Modified residue2251N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q49420 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: F16A009B463EBDAD

FASTA40846,618
        10         20         30         40         50         60 
MSAIKFNPSS FRKNFKWFEN NKNWINFDNA ATSIALDVVA EASKEYYQYF CVNPHNKNPE 

        70         80         90        100        110        120 
INQKLIAIIE ETRDLLAKFF NAKKNEIIFT SSATESLNLF AFGLSSLVKS NDEIILKEDE 

       130        140        150        160        170        180 
HAANVFPWVN LAKENKAKLK IIKKTPNKSW TDAFLKACTP STKLLVITAT SNLFGNSIDY 

       190        200        210        220        230        240 
EKISKHLKKI SPNSFIVVDA VQAVPHHKID ITSANIDFLT FSTHKFYGPT GLGIAFIKSE 

       250        260        270        280        290        300 
LQSRLKPFKL GGDIFKSLDN NFKIIFKEGP SKFEAGTLNI MAIYALNKQL KFMQKEFNFS 

       310        320        330        340        350        360 
EMVFYSKQLK NLAYQLLSQN PNIVLANHDQ DVPIFAFKHK YINSADLATF LNIKKIIVRQ 

       370        380        390        400 
GSICVGKFKN KESFLRVSLL HYNTKEELLY LEKLLKTSKN SIINELIY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71561.1.
U02256 Genomic DNA. Translation: AAD12521.1.
PIRB64237.
RefSeqNP_073006.1. NC_000908.2.

3D structure databases

ProteinModelPortalQ49420.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_336.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71561; AAC71561; MG_336.
GeneID875461.
KEGGmge:MG_336.
PATRIC20010232. VBIMycGen98045_0393.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0520.
KOK11717.
OMAFRQAFPY.
OrthoDBEOG68DD0M.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-386-MONOMER.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCSD_MYCGE
AccessionPrimary (citable) accession number: Q49420
Secondary accession number(s): Q49361
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names