ID   ESL2_MYCGE              Reviewed;         268 AA.
AC   Q49418;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   27-MAR-2024, entry version 110.
DE   RecName: Full=Putative esterase/lipase 2;
DE            EC=3.1.-.-;
GN   OrderedLocusNames=MG327;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae;
OC   Mycoplasmoides.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- SIMILARITY: Belongs to the lipase/esterase LIP3/BchO family.
CC       {ECO:0000305}.
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DR   EMBL; L43967; AAC71551.1; -; Genomic_DNA.
DR   PIR; B64236; B64236.
DR   RefSeq; WP_010869433.1; NC_000908.2.
DR   AlphaFoldDB; Q49418; -.
DR   SMR; Q49418; -.
DR   STRING; 243273.MG_327; -.
DR   ESTHER; mycge-esl2; AlphaBeta_hydrolase.
DR   KEGG; mge:MG_327; -.
DR   eggNOG; COG2267; Bacteria.
DR   HOGENOM; CLU_020336_41_1_14; -.
DR   InParanoid; Q49418; -.
DR   OrthoDB; 403987at2; -.
DR   BioCyc; MGEN243273:G1GJ2-409-MONOMER; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR43689:SF53; ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR43689; HYDROLASE; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..268
FT                   /note="Putative esterase/lipase 2"
FT                   /id="PRO_0000207076"
FT   ACT_SITE        29
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        98
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   268 AA;  30700 MW;  C8DFADB6A41D6087 CRC64;
     MLTSNKNTLF NSIFAFKPKK RKNVFIFLHG FGSEYASFSR IFSLFKKKKW PFFTFNFPGH
     GDNESTDTDQ LKLNHFVDLV CDFIVQKKLN NVILIGHSMG GAVAVLVNKV IPLKIKALIL
     VAPMNQTSFS VNKKRILDTF FKRNNSNHKD FVEHEEKRKS LLKIAINAFK KRTTFKTLYS
     DMVQNAKYGN DSLERAYEMI GNKPTLVILG ANDIVTPTKA SVDYLANKSD KIIFKVIDGV
     GHSPHDSAPK LFFDYVLEFL DNLKKQRY
//