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Q49400

- Y184_MYCGE

UniProt

Q49400 - Y184_MYCGE

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Protein

Uncharacterized adenine-specific methylase MG184

Gene

MG184

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
  2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-193-MONOMER.

Protein family/group databases

REBASEi78740. M.MgeORF184P.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized adenine-specific methylase MG184 (EC:2.1.1.72)
Alternative name(s):
M.MgeORF184P
Gene namesi
Ordered Locus Names:MG184
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317Uncharacterized adenine-specific methylase MG184PRO_0000088015Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_184.

Family & Domainsi

Sequence similaritiesi

Belongs to the N(4)/N(6)-methyltransferase family.Curated

Phylogenomic databases

eggNOGiNOG10100.
KOiK00571.
OMAiPNNCLWL.
OrthoDBiEOG60CWHX.

Family and domain databases

InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR025247. EcoRI_methylase.
[Graphical view]
PfamiPF13651. EcoRI_methylase. 2 hits.
[Graphical view]
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49400-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHHFNRAKKA KNNEFFTLID EIENEVINYQ KQFANKTIFC NCNDGKNSHF
60 70 80 90 100
FQFFQTNFNQ LQLKKLIGFS FNNLSQADKF TFDGNKVTKT KLKGNGDFSS
110 120 130 140 150
DESIEVLKQA DIVVTNPPFS LFQSFIDLLI QHNKQFLVLG LNAAVSYNHI
160 170 180 190 200
FTYFKTNKLW FGYTVNKTMS FSVNSDYQLY NPKTSNFFTK NGKCFQKIAG
210 220 230 240 250
ISWFTNLGKP HYNPFLNTNC FYKNNEKNYP KFDWYDAIYV NKIKNIPMDW
260 270 280 290 300
NGLMGVPLTF LNCYNPKQFE LVDCLANPYA TLDTLKTNAF VKLNQGDVRN
310
VNGKRRYVRV IIKKQQI
Length:317
Mass (Da):37,053
Last modified:November 1, 1996 - v1
Checksum:i7CBF45151ACD0B57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71403.1.
U02115 Genomic DNA. Translation: AAD12389.1.
PIRiD64220.
RefSeqiNP_072847.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71403; AAC71403; MG_184.
GeneIDi875719.
KEGGimge:MG_184.
PATRICi20009800. VBIMycGen98045_0206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71403.1 .
U02115 Genomic DNA. Translation: AAD12389.1 .
PIRi D64220.
RefSeqi NP_072847.1. NC_000908.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_184.

Protein family/group databases

REBASEi 78740. M.MgeORF184P.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71403 ; AAC71403 ; MG_184 .
GeneIDi 875719.
KEGGi mge:MG_184.
PATRICi 20009800. VBIMycGen98045_0206.

Phylogenomic databases

eggNOGi NOG10100.
KOi K00571.
OMAi PNNCLWL.
OrthoDBi EOG60CWHX.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-193-MONOMER.

Family and domain databases

InterProi IPR002052. DNA_methylase_N6_adenine_CS.
IPR025247. EcoRI_methylase.
[Graphical view ]
Pfami PF13651. EcoRI_methylase. 2 hits.
[Graphical view ]
PROSITEi PS00092. N6_MTASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 174-240.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiY184_MYCGE
AccessioniPrimary (citable) accession number: Q49400
Secondary accession number(s): Q49252
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 1, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3