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Q49400

- Y184_MYCGE

UniProt

Q49400 - Y184_MYCGE

Protein

Uncharacterized adenine-specific methylase MG184

Gene

MG184

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

    GO - Molecular functioni

    1. nucleic acid binding Source: InterPro
    2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-193-MONOMER.

    Protein family/group databases

    REBASEi78740. M.MgeORF184P.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized adenine-specific methylase MG184 (EC:2.1.1.72)
    Alternative name(s):
    M.MgeORF184P
    Gene namesi
    Ordered Locus Names:MG184
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 317317Uncharacterized adenine-specific methylase MG184PRO_0000088015Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243273.MG_184.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the N(4)/N(6)-methyltransferase family.Curated

    Phylogenomic databases

    eggNOGiNOG10100.
    KOiK00571.
    OMAiPNNCLWL.
    OrthoDBiEOG60CWHX.

    Family and domain databases

    InterProiIPR002052. DNA_methylase_N6_adenine_CS.
    IPR025247. EcoRI_methylase.
    [Graphical view]
    PfamiPF13651. EcoRI_methylase. 2 hits.
    [Graphical view]
    PROSITEiPS00092. N6_MTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q49400-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHHFNRAKKA KNNEFFTLID EIENEVINYQ KQFANKTIFC NCNDGKNSHF    50
    FQFFQTNFNQ LQLKKLIGFS FNNLSQADKF TFDGNKVTKT KLKGNGDFSS 100
    DESIEVLKQA DIVVTNPPFS LFQSFIDLLI QHNKQFLVLG LNAAVSYNHI 150
    FTYFKTNKLW FGYTVNKTMS FSVNSDYQLY NPKTSNFFTK NGKCFQKIAG 200
    ISWFTNLGKP HYNPFLNTNC FYKNNEKNYP KFDWYDAIYV NKIKNIPMDW 250
    NGLMGVPLTF LNCYNPKQFE LVDCLANPYA TLDTLKTNAF VKLNQGDVRN 300
    VNGKRRYVRV IIKKQQI 317
    Length:317
    Mass (Da):37,053
    Last modified:November 1, 1996 - v1
    Checksum:i7CBF45151ACD0B57
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71403.1.
    U02115 Genomic DNA. Translation: AAD12389.1.
    PIRiD64220.
    RefSeqiNP_072847.1. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71403; AAC71403; MG_184.
    GeneIDi875719.
    KEGGimge:MG_184.
    PATRICi20009800. VBIMycGen98045_0206.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71403.1 .
    U02115 Genomic DNA. Translation: AAD12389.1 .
    PIRi D64220.
    RefSeqi NP_072847.1. NC_000908.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_184.

    Protein family/group databases

    REBASEi 78740. M.MgeORF184P.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71403 ; AAC71403 ; MG_184 .
    GeneIDi 875719.
    KEGGi mge:MG_184.
    PATRICi 20009800. VBIMycGen98045_0206.

    Phylogenomic databases

    eggNOGi NOG10100.
    KOi K00571.
    OMAi PNNCLWL.
    OrthoDBi EOG60CWHX.

    Enzyme and pathway databases

    BioCyci MGEN243273:GH2R-193-MONOMER.

    Family and domain databases

    InterProi IPR002052. DNA_methylase_N6_adenine_CS.
    IPR025247. EcoRI_methylase.
    [Graphical view ]
    Pfami PF13651. EcoRI_methylase. 2 hits.
    [Graphical view ]
    PROSITEi PS00092. N6_MTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.
    2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
      Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
      J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 174-240.
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiY184_MYCGE
    AccessioniPrimary (citable) accession number: Q49400
    Secondary accession number(s): Q49252
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3