Reviewed,
UniProtKB/Swiss-Prot Q493W4 (PSD_BLOPB)
Last modified
February 9, 2010.
Version 25.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Phosphatidylserine decarboxylase proenzyme EC=4.1.1.65 Cleaved into the following 2 chains: 1- Recommended name: Phosphatidylserine decarboxylase alpha chain 2- Recommended name: Phosphatidylserine decarboxylase beta chain | ||||
| Gene names |
| ||||
| Organism | Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 291272 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia |
Protein attributes
| Sequence length | 295 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662 |
| Cofactor | Pyruvoyl group By similarity. HAMAP MF_00662 |
| Pathway | Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662 |
| Sequence similarities | Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Phospholipid biosynthesis |
| Ligand | Pyruvate |
| Molecular function | Decarboxylase Lyase |
| PTM | Zymogen |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 257 | 257 | Phosphatidylserine decarboxylase beta chain By similarity | PRO_0000262095 | |||||
| Chain | 258 – 295 | 38 | Phosphatidylserine decarboxylase alpha chain By similarity | PRO_0000262096 | |||||
Sites | |||||||||
| Site | 257 – 258 | 2 | Cleavage (non-hydrolytic) By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 258 | 1 | Pyruvic acid (Ser) By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000016 Genomic DNA. Translation: AAZ40720.1. |
| RefSeq | YP_277592.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q493W4. |
Genome annotation databases | |
| GeneID | 3563046. |
| GenomeReviews | Gene locus BPEN_076 in contig CP000016_GR. |
| KEGG | bpn:BPEN_076. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0688. |
| HOGENOM | HBG302256. |
| OMA | ALFSVNP. |
Enzyme and pathway databases | |
| BioCyc | CBLO291272:BPEN_076-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00662. PS_decarb_type1. [Tree] |
| InterPro | IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view] |
| PANTHER | PTHR10067. PS_decarb. 1 hit. |
| Pfam | PF02666. PS_Dcarbxylase. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00163. PS_decarb. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PSD_BLOPB | ||||||||
| Accession | Primary (citable) accession number: Q493W4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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