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Q493W4 (PSD_BLOPB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BPEN_076
OrganismBlochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]
Taxonomic identifier291272 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262095
Chain258 – 29538Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262096

Sites

Site257 – 2582Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2581Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q493W4 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 80470027334DDA4D

FASTA29533,606
        10         20         30         40         50         60 
MLEKIQILLQ YLLPKYWITY LVGLGASWKG GWITRYAILL FIHIYKIDMK ESDKPNLTDY 

        70         80         90        100        110        120 
ATFNAFFTRK LHKNARPIDT NPSTLIIPAD GIITQIGKIN QTNIFRVKNA PYHLDGLLAG 

       130        140        150        160        170        180 
HDNIIDYFIN GSFVIIYIPP QNCHRIYMPC TGTLREVLYI PGNLFSVHPK ITKNMPNIFS 

       190        200        210        220        230        240 
RNERVICLFE TDFGYMAQIL IGAIIVGSIE TTWLGTITPP REGIVRHWRY SSNNTNTDAD 

       250        260        270        280        290 
DSIILQKGHE MGLFKLGSTV INLFGDKKVI LNNLLQPYDI ARIGMPLAHG HSQKK

« Hide

References

[1]"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects."
Degnan P.H., Lazarus A.B., Wernegreen J.J.
Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BPEN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000016 Genomic DNA. Translation: AAZ40720.1.
RefSeqYP_277592.1. NC_007292.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ493W4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3563046.
GenomeReviewsGene locus BPEN_076 in contig CP000016_GR.
KEGGbpn:BPEN_076.
PATRIC31965038. VBICanBlo110049_0072.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMASMATVWH.
PhylomeDBQ493W4.
ProtClustDBPRK00044.

Enzyme and pathway databases

BioCycCBLO291272:BPEN_076-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BLOPB
AccessionPrimary (citable) accession number: Q493W4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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