Reviewed, UniProtKB/Swiss-Prot Q493U0 (GLMM_BLOPB)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BPEN_103

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	453 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 453	453	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147853
Sites
	Active site	105	1	Phosphoserine intermediate By similarity
	Metal binding	105	1	Magnesium; via phosphate group By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
	Metal binding	248	1	Magnesium By similarity
Amino acid modifications
	Modified residue	105	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q493U0-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 6590787DE8E359A4	FASTA	453	49,335
	10 20 30 40 50 60 MKRRKYFGTD GIRGKVGSMP ITPDFILKLG WAAGKVLSRF SGGRSNYIII GKDTRISGYM 70 80 90 100 110 120 LESALESGLA AAGLSAALTG PMPTPAIAYL TRTFRAEAGI VISASHNPFY DNGIKFFSIK 130 140 150 160 170 180 GTKLDNEVEH SIEIELEKCL TCVDPKELGK ASRIVDAAGR YIEFCKGTFP AHLSLRKLKI 190 200 210 220 230 240 IVDCANGATY HIAPSVFREL GANVTTIACR PNGVNINKEC GTTDIRQLRA HVLAKKADLG 250 260 270 280 290 300 IAYDGDGDRV IMVDHFGNKV DGDQMLYIIA REKLHCKQLT GGIVGTLMSN MGLVLALKQL 310 320 330 340 350 360 NIPFIRSNVG DRCVLAMLKK QGWNIGGENS GHIVLLDKTT TGDGIIVALQ VLSAMVNNCV 370 380 390 400 410 420 SLHELCNDVS LLPQILVNVY CSSIKSPLES DLVRKETKAV EQELSEQGRV LLRQSGTEPY 430 440 450 IRIMVEGNCC YGKILYLANR IASVIRSEIK SIQ

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000016 Genomic DNA. Translation: AAZ40745.1.
RefSeq	YP_277618.1.
3D structure databases
SMR	Q493U0. Positions 5-446.
ModBase	Search...
Protein-protein interaction databases
STRING	Q493U0.
Genome annotation databases
GeneID	3563184.
GenomeReviews	Gene locus BPEN_103 in contig CP000016_GR.
KEGG	bpn:BPEN_103.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	VHDRYIE.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_103-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BLOPB

Accession

Primary (citable) accession number: Q493U0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	September 13, 2005
Last modified:	February 9, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)