ID   DAPB_BLOPB              Reviewed;         282 AA.
AC   Q493S0;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 27.
DE   RecName: Full=Dihydrodipicolinate reductase;
DE            Short=DHPR;
DE            EC=1.3.1.26;
GN   Name=dapB; OrderedLocusNames=BPEN_125;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- CATALYTIC ACTIVITY: 2,3,4,5-tetrahydrodipicolinate + NAD(P)(+) =
CC       2,3-dihydrodipicolinate + NAD(P)H.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; tetrahydrodipicolinate from L-aspartate: step 4/4.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the dihydrodipicolinate reductase family.
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DR   EMBL; CP000016; AAZ40765.1; -; Genomic_DNA.
DR   RefSeq; YP_277638.1; -.
DR   GeneID; 3563160; -.
DR   GenomeReviews; CP000016_GR; BPEN_125.
DR   KEGG; bpn:BPEN_125; -.
DR   HOGENOM; Q493S0; -.
DR   OMA; Q493S0; TIGFSTI.
DR   BioCyc; CBLO291272:BPEN_125-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0008839; F:dihydrodipicolinate reductase activity; IEA:HAMAP.
DR   GO; GO:0019877; P:diaminopimelate biosynthetic process; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00102; -; 1.
DR   InterPro; IPR000846; DapB.
DR   InterPro; IPR011770; DapB_bac/pln.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR20836; DapB_bac/pln; 1.
DR   Pfam; PF05173; DapB_C; 1.
DR   Pfam; PF01113; DapB_N; 1.
DR   ProDom; PD004105; DapB; 1.
DR   TIGRFAMs; TIGR00036; dapB; 1.
DR   PROSITE; PS01298; DAPB; FALSE_NEG.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm;
KW   Diaminopimelate biosynthesis; Lysine biosynthesis; NADP;
KW   Oxidoreductase.
FT   CHAIN         1    282       Dihydrodipicolinate reductase.
FT                                /FTId=PRO_0000228329.
SQ   SEQUENCE   282 AA;  30864 MW;  5309FAC65A17FA81 CRC64;
     MSDTPLRIAV TGVTGRMGKE IVTCIVKEEK QFSQEIVLGA AITRLNTNIC GMDAGILINT
     DALGIEITDN LESIKDNFDV LVDFTAPDIS IEYLKFCVNN NKNIVIGTTG FNQIHKNIIL
     NASHKIGIVF SSNFSIGVAL ISKLLHKITQ VIGNTSDISI IETHHNRKRD IPSGTSLTMQ
     NIIVNALRSI HSNRIIDSNL DSTTYSPASS YKDILIHSIR AGDVVGEHTV LFAGPGERLE
     ITHKASDRLI FAHGALRAAF WVGRDKIGLF DISDILEMDT LL
//