Q493S0 (DAPB_BLOPB) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 47.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Dihydrodipicolinate reductase Short name=DHPR EC=1.3.1.26 | ||||
| Gene names |
| ||||
| Organism | Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 291272 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia |
Protein attributes
| Sequence length | 282 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | (S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102 |
| Pathway | Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102 |
| Subunit structure | Homotetramer By similarity. HAMAP MF_00102 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00102. |
| Sequence similarities | Belongs to the dihydrodipicolinate reductase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Diaminopimelate biosynthesis Lysine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | diaminopimelate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | NADPH binding Inferred from electronic annotation. Source: InterPro dihydrodipicolinate reductase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 282 | 282 | Dihydrodipicolinate reductase HAMAP MF_00102 | PRO_0000228329 | |||
Sequences
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References
| [1] | "Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BPEN. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000016 Genomic DNA. Translation: AAZ40765.1. |
| RefSeq | YP_277638.1. NC_007292.1. |
3D structure databases | |
| ProteinModelPortal | Q493S0. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q493S0. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3563160. |
| GenomeReviews | Gene locus BPEN_125 in contig CP000016_GR. |
| KEGG | bpn:BPEN_125. |
| PATRIC | 31965141. VBICanBlo110049_0120. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0289. |
| HOGENOM | HBG594002. |
| OMA | YNNENIE. |
| PhylomeDB | Q493S0. |
| ProtClustDB | PRK00048. |
Enzyme and pathway databases | |
| BioCyc | CBLO291272:BPEN_125-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00102. DapB. [Tree] |
| InterPro | IPR022663. DapB_C. IPR000846. DapB_N. IPR011770. Dihydrodipicolinate_Rdtase. IPR023940. Dihydrodipicolinate_Rdtase_bac. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| KO | K00215. |
| PANTHER | PTHR20836. DapB_bac/pln. 1 hit. |
| Pfam | PF05173. DapB_C. 1 hit. PF01113. DapB_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000161. DHPR. 1 hit. |
| TIGRFAMs | TIGR00036. DapB. 1 hit. |
| PROSITE | PS01298. DAPB. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DAPB_BLOPB | ||||||||
| Accession | Primary (citable) accession number: Q493S0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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