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Protein

UPF0053 protein MG146

Gene

MG146

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-154-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0053 protein MG146
Alternative name(s):
VXpSPT7_orf424
Gene namesi
Ordered Locus Names:MG146
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721HelicalSequence AnalysisAdd
BLAST
Transmembranei71 – 9121HelicalSequence AnalysisAdd
BLAST
Transmembranei101 – 12121HelicalSequence AnalysisAdd
BLAST
Transmembranei135 – 15521HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 424424UPF0053 protein MG146PRO_0000088378Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ49399.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 190177DUF21Add
BLAST
Domaini210 – 27061CBS 1PROSITE-ProRule annotationAdd
BLAST
Domaini272 – 33261CBS 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the UPF0053 family.Curated
Contains 2 CBS domains.PROSITE-ProRule annotation
Contains 1 DUF21 domain.Curated

Keywords - Domaini

CBS domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1253.
OMAiFFNKWIK.
OrthoDBiEOG64FKB6.

Family and domain databases

InterProiIPR000644. CBS_dom.
IPR002550. DUF21.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF01595. DUF21. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
[Graphical view]
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49399-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSAPSGLTL TVIILSIILL AFISTVVSAY ETAITSLTPY RWKNYIKTNN
60 70 80 90 100
KQDKLSTKII NHFQNHYSSC LITILITNNI VAIMVSNILF LALEQTIKNE
110 120 130 140 150
LLSSVLNLVV SGVLIVSFCE ILPKTLGRIN VIRTLVLFAY LVYFFYLIFW
160 170 180 190 200
PITKLTSLIL KKYENPLPVS RKDVYYFIDE IEQNGLFSKE DSLLIKKTLI
210 220 230 240 250
FDQVLVKKVM IKWKKVAYCY LNDSINLIAK QFLQRQFSRM PVVDKTTNKI
260 270 280 290 300
VGFIHLKDFF TAKEANPKSL DLNQLLYPVV LVQDSTPIKQ ALRQMRLNRA
310 320 330 340 350
HLAVVNDKHE KTIGIVSMED IIEELVGEIY DEHDDIQPIQ VLDENVWLVL
360 370 380 390 400
PNVKAAYFFN KWIKPDLVKS KNITIQHYLA SLDNDSFACQ NKLDTPLFSV
410 420
EVIADSEDKT KILYEIRKKS DVIA
Length:424
Mass (Da):48,720
Last modified:November 1, 1996 - v1
Checksum:iA361AAE5B995DA87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71364.1.
PIRiB64216.
RefSeqiWP_010869353.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71364; AAC71364; MG_146.
KEGGimge:MG_146.
PATRICi20009722. VBIMycGen98045_0167.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71364.1.
PIRiB64216.
RefSeqiWP_010869353.1. NC_000908.2.

3D structure databases

ProteinModelPortaliQ49399.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71364; AAC71364; MG_146.
KEGGimge:MG_146.
PATRICi20009722. VBIMycGen98045_0167.

Phylogenomic databases

eggNOGiCOG1253.
OMAiFFNKWIK.
OrthoDBiEOG64FKB6.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-154-MONOMER.

Family and domain databases

InterProiIPR000644. CBS_dom.
IPR002550. DUF21.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF01595. DUF21. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
[Graphical view]
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiY146_MYCGE
AccessioniPrimary (citable) accession number: Q49399
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: July 22, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.