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Q49398

- GLF_MYCGE

UniProt

Q49398 - GLF_MYCGE

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Protein

UDP-galactopyranose mutase

Gene

glf

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate.By similarity

Catalytic activityi

UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose.

Cofactori

FADBy similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei31 – 311FADBy similarity
Binding sitei58 – 581FAD; via amide nitrogenBy similarity
Binding sitei176 – 1761UDP-GalPBy similarity
Binding sitei180 – 1801UDP-GalPBy similarity
Binding sitei205 – 2051UDP-GalPBy similarity
Binding sitei302 – 3021UDP-GalPBy similarity
Binding sitei311 – 3111UDP-GalPBy similarity
Binding sitei350 – 3501UDP-GalPBy similarity
Binding sitei379 – 3791FADBy similarity
Binding sitei385 – 3851UDP-GalPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi50 – 512FADBy similarity
Nucleotide bindingi77 – 782FADBy similarity
Nucleotide bindingi386 – 3916FADBy similarity

GO - Molecular functioni

  1. oxidoreductase activity Source: InterPro
  2. UDP-galactopyranose mutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-141-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-galactopyranose mutase (EC:5.4.99.9)
Short name:
UGM
Alternative name(s):
UDP-GALP mutase
Uridine 5-diphosphate galactopyranose mutase
Gene namesi
Name:glf
Ordered Locus Names:MG137
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404UDP-galactopyranose mutasePRO_0000087509Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_137.

Structurei

3D structure databases

ProteinModelPortaliQ49398.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0562.
KOiK01854.
OMAiGKQWQTD.
OrthoDBiEOG62K1X2.

Family and domain databases

Gene3Di3.40.50.720. 3 hits.
InterProiIPR016040. NAD(P)-bd_dom.
IPR003042. Rng_hydrolase-like.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view]
PANTHERiPTHR21197. PTHR21197. 1 hit.
PfamiPF03275. GLF. 1 hit.
[Graphical view]
PRINTSiPR00420. RNGMNOXGNASE.
TIGRFAMsiTIGR00031. UDP-GALP_mutase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q49398-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNVILSVMLF SSPSCVNINS FDILIVGAGI SGIVLANILA NHNKRVLIVE
60 70 80 90 100
KRDHIGGNCY DKVDSKTQLL FHQYGPHIFH TNNQTVINFI SPFFELNNYH
110 120 130 140 150
HRVGLKLKNN LDLTLPFDFQ QIYKLMGKDG RKLVSFFKEN FSLNTHLSLA
160 170 180 190 200
ELQLIDNPLA QKLYQFLISN VYKPYSVKMW GLPFAMINEN VINRVKIVLS
210 220 230 240 250
EQSSYFPDAI IQGLPKSGYT NSFLKMLANP LIDVQLNCKD NLLVYQDEKL
260 270 280 290 300
FFNNNLIEKP VVYCGLIDKL FNFCFGHLQY RSLAFSWKRF NQKKYQTYPV
310 320 330 340 350
VNMPLAKSIT RSVEYKQLTN QGSFKPQTIV SFETPGSYAI NDPRFNEPYY
360 370 380 390 400
PINNTLNDTL FKKYWKKASK LKNLHLLGRL ATYQYIDMDK AILLSIKKAQ

QLLS
Length:404
Mass (Da):46,661
Last modified:November 1, 1996 - v1
Checksum:i67B8DAB814A3A680
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71354.1.
PIRiB64215.
RefSeqiNP_072799.1. NC_000908.2.
WP_010869349.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71354; AAC71354; MG_137.
GeneIDi875453.
KEGGimge:MG_137.
PATRICi20009680. VBIMycGen98045_0149.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71354.1 .
PIRi B64215.
RefSeqi NP_072799.1. NC_000908.2.
WP_010869349.1. NC_000908.2.

3D structure databases

ProteinModelPortali Q49398.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_137.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71354 ; AAC71354 ; MG_137 .
GeneIDi 875453.
KEGGi mge:MG_137.
PATRICi 20009680. VBIMycGen98045_0149.

Phylogenomic databases

eggNOGi COG0562.
KOi K01854.
OMAi GKQWQTD.
OrthoDBi EOG62K1X2.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-141-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 3 hits.
InterProi IPR016040. NAD(P)-bd_dom.
IPR003042. Rng_hydrolase-like.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view ]
PANTHERi PTHR21197. PTHR21197. 1 hit.
Pfami PF03275. GLF. 1 hit.
[Graphical view ]
PRINTSi PR00420. RNGMNOXGNASE.
TIGRFAMsi TIGR00031. UDP-GALP_mutase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiGLF_MYCGE
AccessioniPrimary (citable) accession number: Q49398
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3