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Q49398 (GLF_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-galactopyranose mutase

Short name=UGM
EC=5.4.99.9
Alternative name(s):
UDP-GALP mutase
Uridine 5-diphosphate galactopyranose mutase
Gene names
Name:glf
Ordered Locus Names:MG137
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate By similarity.

Catalytic activity

UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose.

Cofactor

FAD By similarity.

Sequence similarities

Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionUDP-galactopyranose mutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 404404UDP-galactopyranose mutase
PRO_0000087509

Regions

Nucleotide binding50 – 512FAD By similarity
Nucleotide binding77 – 782FAD By similarity
Nucleotide binding386 – 3916FAD By similarity

Sites

Binding site311FAD By similarity
Binding site581FAD; via amide nitrogen By similarity
Binding site1761UDP-GalP By similarity
Binding site1801UDP-GalP By similarity
Binding site2051UDP-GalP By similarity
Binding site3021UDP-GalP By similarity
Binding site3111UDP-GalP By similarity
Binding site3501UDP-GalP By similarity
Binding site3791FAD By similarity
Binding site3851UDP-GalP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q49398 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 67B8DAB814A3A680

FASTA40446,661
        10         20         30         40         50         60 
MNVILSVMLF SSPSCVNINS FDILIVGAGI SGIVLANILA NHNKRVLIVE KRDHIGGNCY 

        70         80         90        100        110        120 
DKVDSKTQLL FHQYGPHIFH TNNQTVINFI SPFFELNNYH HRVGLKLKNN LDLTLPFDFQ 

       130        140        150        160        170        180 
QIYKLMGKDG RKLVSFFKEN FSLNTHLSLA ELQLIDNPLA QKLYQFLISN VYKPYSVKMW 

       190        200        210        220        230        240 
GLPFAMINEN VINRVKIVLS EQSSYFPDAI IQGLPKSGYT NSFLKMLANP LIDVQLNCKD 

       250        260        270        280        290        300 
NLLVYQDEKL FFNNNLIEKP VVYCGLIDKL FNFCFGHLQY RSLAFSWKRF NQKKYQTYPV 

       310        320        330        340        350        360 
VNMPLAKSIT RSVEYKQLTN QGSFKPQTIV SFETPGSYAI NDPRFNEPYY PINNTLNDTL 

       370        380        390        400 
FKKYWKKASK LKNLHLLGRL ATYQYIDMDK AILLSIKKAQ QLLS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71354.1.
PIRB64215.
RefSeqNP_072799.1. NC_000908.2.

3D structure databases

ProteinModelPortalQ49398.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_137.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71354; AAC71354; MG_137.
GeneID875453.
KEGGmge:MG_137.
PATRIC20009680. VBIMycGen98045_0149.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0562.
KOK01854.
OMAEPGRNEP.
OrthoDBEOG62K1X2.
ProtClustDBCLSK542169.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-141-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 3 hits.
InterProIPR016040. NAD(P)-bd_dom.
IPR003042. Rng_hydrolase-like.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view]
PANTHERPTHR21197. PTHR21197. 1 hit.
PfamPF03275. GLF. 1 hit.
[Graphical view]
PRINTSPR00420. RNGMNOXGNASE.
TIGRFAMsTIGR00031. UDP-GALP_mutase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLF_MYCGE
AccessionPrimary (citable) accession number: Q49398
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names