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Protein

UDP-galactopyranose mutase

Gene

glf

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate.By similarity

Catalytic activityi

UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose.

Cofactori

FADBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei31FADBy similarity1
Binding sitei58FAD; via amide nitrogenBy similarity1
Binding sitei176UDP-GalPBy similarity1
Binding sitei180UDP-GalPBy similarity1
Binding sitei205UDP-GalPBy similarity1
Binding sitei302UDP-GalPBy similarity1
Binding sitei311UDP-GalPBy similarity1
Binding sitei350UDP-GalPBy similarity1
Binding sitei379FADBy similarity1
Binding sitei385UDP-GalPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi50 – 51FADBy similarity2
Nucleotide bindingi77 – 78FADBy similarity2
Nucleotide bindingi386 – 391FADBy similarity6

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-galactopyranose mutase (EC:5.4.99.9)
Short name:
UGM
Alternative name(s):
UDP-GALP mutase
Uridine 5-diphosphate galactopyranose mutase
Gene namesi
Name:glf
Ordered Locus Names:MG137
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000807 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000875091 – 404UDP-galactopyranose mutaseAdd BLAST404

Interactioni

Protein-protein interaction databases

STRINGi243273.MgenG_010200000960.

Structurei

3D structure databases

ProteinModelPortaliQ49398.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107R6R. Bacteria.
COG0562. LUCA.
KOiK01854.
OMAiDDREVWD.
OrthoDBiPOG091H0689.

Family and domain databases

Gene3Di3.40.50.720. 3 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016040. NAD(P)-bd_dom.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view]
PANTHERiPTHR21197. PTHR21197. 1 hit.
PfamiPF03275. GLF. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00031. UDP-GALP_mutase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q49398-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVILSVMLF SSPSCVNINS FDILIVGAGI SGIVLANILA NHNKRVLIVE
60 70 80 90 100
KRDHIGGNCY DKVDSKTQLL FHQYGPHIFH TNNQTVINFI SPFFELNNYH
110 120 130 140 150
HRVGLKLKNN LDLTLPFDFQ QIYKLMGKDG RKLVSFFKEN FSLNTHLSLA
160 170 180 190 200
ELQLIDNPLA QKLYQFLISN VYKPYSVKMW GLPFAMINEN VINRVKIVLS
210 220 230 240 250
EQSSYFPDAI IQGLPKSGYT NSFLKMLANP LIDVQLNCKD NLLVYQDEKL
260 270 280 290 300
FFNNNLIEKP VVYCGLIDKL FNFCFGHLQY RSLAFSWKRF NQKKYQTYPV
310 320 330 340 350
VNMPLAKSIT RSVEYKQLTN QGSFKPQTIV SFETPGSYAI NDPRFNEPYY
360 370 380 390 400
PINNTLNDTL FKKYWKKASK LKNLHLLGRL ATYQYIDMDK AILLSIKKAQ

QLLS
Length:404
Mass (Da):46,661
Last modified:November 1, 1996 - v1
Checksum:i67B8DAB814A3A680
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71354.1.
PIRiB64215.

Genome annotation databases

EnsemblBacteriaiAAC71354; AAC71354; MG_137.
KEGGimge:MG_137.
PATRICi20009680. VBIMycGen98045_0149.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71354.1.
PIRiB64215.

3D structure databases

ProteinModelPortaliQ49398.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MgenG_010200000960.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71354; AAC71354; MG_137.
KEGGimge:MG_137.
PATRICi20009680. VBIMycGen98045_0149.

Phylogenomic databases

eggNOGiENOG4107R6R. Bacteria.
COG0562. LUCA.
KOiK01854.
OMAiDDREVWD.
OrthoDBiPOG091H0689.

Family and domain databases

Gene3Di3.40.50.720. 3 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016040. NAD(P)-bd_dom.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view]
PANTHERiPTHR21197. PTHR21197. 1 hit.
PfamiPF03275. GLF. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00031. UDP-GALP_mutase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLF_MYCGE
AccessioniPrimary (citable) accession number: Q49398
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.