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Q49398

- GLF_MYCGE

UniProt

Q49398 - GLF_MYCGE

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Protein
UDP-galactopyranose mutase
Gene
glf, MG137
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate By similarity.

Catalytic activityi

UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose.

Cofactori

FAD By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei31 – 311FAD By similarity
Binding sitei58 – 581FAD; via amide nitrogen By similarity
Binding sitei176 – 1761UDP-GalP By similarity
Binding sitei180 – 1801UDP-GalP By similarity
Binding sitei205 – 2051UDP-GalP By similarity
Binding sitei302 – 3021UDP-GalP By similarity
Binding sitei311 – 3111UDP-GalP By similarity
Binding sitei350 – 3501UDP-GalP By similarity
Binding sitei379 – 3791FAD By similarity
Binding sitei385 – 3851UDP-GalP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi50 – 512FAD By similarity
Nucleotide bindingi77 – 782FAD By similarity
Nucleotide bindingi386 – 3916FAD By similarity

GO - Molecular functioni

  1. UDP-galactopyranose mutase activity Source: UniProtKB-EC
  2. oxidoreductase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-141-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-galactopyranose mutase (EC:5.4.99.9)
Short name:
UGM
Alternative name(s):
UDP-GALP mutase
Uridine 5-diphosphate galactopyranose mutase
Gene namesi
Name:glf
Ordered Locus Names:MG137
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404UDP-galactopyranose mutase
PRO_0000087509Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_137.

Structurei

3D structure databases

ProteinModelPortaliQ49398.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0562.
KOiK01854.
OMAiGKQWQTD.
OrthoDBiEOG62K1X2.

Family and domain databases

Gene3Di3.40.50.720. 3 hits.
InterProiIPR016040. NAD(P)-bd_dom.
IPR003042. Rng_hydrolase-like.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view]
PANTHERiPTHR21197. PTHR21197. 1 hit.
PfamiPF03275. GLF. 1 hit.
[Graphical view]
PRINTSiPR00420. RNGMNOXGNASE.
TIGRFAMsiTIGR00031. UDP-GALP_mutase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q49398-1 [UniParc]FASTAAdd to Basket

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MNVILSVMLF SSPSCVNINS FDILIVGAGI SGIVLANILA NHNKRVLIVE    50
KRDHIGGNCY DKVDSKTQLL FHQYGPHIFH TNNQTVINFI SPFFELNNYH 100
HRVGLKLKNN LDLTLPFDFQ QIYKLMGKDG RKLVSFFKEN FSLNTHLSLA 150
ELQLIDNPLA QKLYQFLISN VYKPYSVKMW GLPFAMINEN VINRVKIVLS 200
EQSSYFPDAI IQGLPKSGYT NSFLKMLANP LIDVQLNCKD NLLVYQDEKL 250
FFNNNLIEKP VVYCGLIDKL FNFCFGHLQY RSLAFSWKRF NQKKYQTYPV 300
VNMPLAKSIT RSVEYKQLTN QGSFKPQTIV SFETPGSYAI NDPRFNEPYY 350
PINNTLNDTL FKKYWKKASK LKNLHLLGRL ATYQYIDMDK AILLSIKKAQ 400
QLLS 404
Length:404
Mass (Da):46,661
Last modified:November 1, 1996 - v1
Checksum:i67B8DAB814A3A680
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71354.1.
PIRiB64215.
RefSeqiNP_072799.1. NC_000908.2.
WP_010869349.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71354; AAC71354; MG_137.
GeneIDi875453.
KEGGimge:MG_137.
PATRICi20009680. VBIMycGen98045_0149.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71354.1 .
PIRi B64215.
RefSeqi NP_072799.1. NC_000908.2.
WP_010869349.1. NC_000908.2.

3D structure databases

ProteinModelPortali Q49398.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_137.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71354 ; AAC71354 ; MG_137 .
GeneIDi 875453.
KEGGi mge:MG_137.
PATRICi 20009680. VBIMycGen98045_0149.

Phylogenomic databases

eggNOGi COG0562.
KOi K01854.
OMAi GKQWQTD.
OrthoDBi EOG62K1X2.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-141-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 3 hits.
InterProi IPR016040. NAD(P)-bd_dom.
IPR003042. Rng_hydrolase-like.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view ]
PANTHERi PTHR21197. PTHR21197. 1 hit.
Pfami PF03275. GLF. 1 hit.
[Graphical view ]
PRINTSi PR00420. RNGMNOXGNASE.
TIGRFAMsi TIGR00031. UDP-GALP_mutase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiGLF_MYCGE
AccessioniPrimary (citable) accession number: Q49398
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 3, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi