Reviewed, UniProtKB/Swiss-Prot Q49398 (GLF_MYCGE)

Names and origin

Protein names

Recommended name:
    UDP-galactopyranose mutase
    EC=5.4.99.9

Gene names

Name:	glf
Ordered Locus Names:	MG137

Organism

Mycoplasma genitalium [Complete proteome] [HAMAP]

Taxonomic identifier

2097 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate By similarity.
Catalytic activity	UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.
Cofactor	FAD By similarity.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	UDP-galactopyranose mutase activity Inferred from electronic annotation. Source: EC binding Inferred from electronic annotation. Source: InterPro electron carrier activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	UDP-galactopyranose mutase		PRO_0000087509
Regions
	Nucleotide binding	22 – 50	29	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q49398-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 67B8DAB814A3A680	FASTA	404	46,661
	10 20 30 40 50 60 MNVILSVMLF SSPSCVNINS FDILIVGAGI SGIVLANILA NHNKRVLIVE KRDHIGGNCY 70 80 90 100 110 120 DKVDSKTQLL FHQYGPHIFH TNNQTVINFI SPFFELNNYH HRVGLKLKNN LDLTLPFDFQ 130 140 150 160 170 180 QIYKLMGKDG RKLVSFFKEN FSLNTHLSLA ELQLIDNPLA QKLYQFLISN VYKPYSVKMW 190 200 210 220 230 240 GLPFAMINEN VINRVKIVLS EQSSYFPDAI IQGLPKSGYT NSFLKMLANP LIDVQLNCKD 250 260 270 280 290 300 NLLVYQDEKL FFNNNLIEKP VVYCGLIDKL FNFCFGHLQY RSLAFSWKRF NQKKYQTYPV 310 320 330 340 350 360 VNMPLAKSIT RSVEYKQLTN QGSFKPQTIV SFETPGSYAI NDPRFNEPYY PINNTLNDTL 370 380 390 400 FKKYWKKASK LKNLHLLGRL ATYQYIDMDK AILLSIKKAQ QLLS

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L43967 Genomic DNA. Translation: AAC71354.1.
PIR	B64215.
RefSeq	NP_072799.1.
3D structure databases
HSSP	HSSP built from PDB template 1I8T based on UniProtKB P37747.
ModBase	Search...
Genome annotation databases
GeneID	875453.
GenomeReviews	Gene locus MG137 in contig L43967_GR.
KEGG	mge:MG_137.
TIGR	MG137.
Phylogenomic databases
HOGENOM	Q49398.
OMA	Q49398. KFFRGYT.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_137-MON.
BRENDA	5.4.99.9. 110.
Family and domain databases
InterPro	IPR002937. Amino_oxidase. IPR016040. NAD(P)-bd_dom. IPR003042. Rng_hydrolase-like. IPR004379. UDP-GALP_mutase. IPR015899. UDP-GalPyranose_mutase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF01593. Amino_oxidase. 1 hit. PF03275. GLF. 1 hit. [Graphical view]
PRINTS	PR00420. RNGMNOXGNASE.
TIGRFAMs	TIGR00031. UDP-GALP_mutase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLF_MYCGE

Accession

Primary (citable) accession number: Q49398

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)