Reviewed, UniProtKB/Swiss-Prot Q49396 (FRUK_MYCGE)

Names and origin

Protein names

Recommended name:
    Putative 1-phosphofructokinase
    EC=2.7.1.56
Alternative name(s):
    Fructose 1-phosphate kinase

Gene names

Name:	fruK
Ordered Locus Names:	MG063

Organism

Mycoplasma genitalium [Complete proteome] [HAMAP]

Taxonomic identifier

2097 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.
Sequence similarities	Belongs to the carbohydrate kinase pfkB family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	1-phosphofructokinase activity Inferred from electronic annotation. Source: EC ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Putative 1-phosphofructokinase		PRO_0000080068

Sequences

	Sequence		Length	Mass (Da)
	Q49396-1 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 7C979CAE5DFEB795	FASTA	300	33,521
	10 20 30 40 50 60 MQNITKESKI WIVNYACAID YYVDLNKQKN SVLIPGGKGI NVAIVMKSLG FDPTVITFLG 70 80 90 100 110 120 QPTKNLFLEL VKPYDLNIVS FISETKTRIN LKLLKDEKTT EINDLSPLIT DANLTELLTF 130 140 150 160 170 180 LKANVKNNDL VIINGRFKFE ALEKVLNLVF TLTENVVIDV DESKMLTLLN QSKPLVMKPN 190 200 210 220 230 240 IDEFQTMINT FFHDQQSLIA AIKKFHYCKL LLLSDGDKGA YLFDQNKLLF VSSITPKQVV 250 260 270 280 290 300 STTGAGDTLL AVFLANLILK VDLKTALIKA TNYASATISK LGVVDSKDKI SVITPKSYYL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.
[2]	"A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed: 8253680] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 167-253. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L43967 Genomic DNA. Translation: AAC71280.1. Different initiation. U01777 Genomic DNA. Translation: AAD10597.1.
RefSeq	NP_072725.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	875512.
GenomeReviews	Gene locus MG063 in contig L43967_GR.
KEGG	mge:MG_063.
TIGR	MG063.
Phylogenomic databases
HOGENOM	Q49396.
OMA	TACAGDA
Enzyme and pathway databases
BioCyc	MGEN243273:MG_063-MON.
BRENDA	2.7.1.56. 110.
Family and domain databases
InterPro	IPR011611. Carb/pur_kinase. IPR002173. Carboh/pur_kinase_PfkB_CS. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PROSITE	PS00583. PFKB_KINASES_1. 1 hit. PS00584. PFKB_KINASES_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FRUK_MYCGE

Accession

Primary (citable) accession number: Q49396
Secondary accession number(s): Q49226

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 3, 2009
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)