Reviewed, UniProtKB/Swiss-Prot Q492W6 (6PGL_BLOPB)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	BPEN_351

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 337	337	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000291464

Sequences

	Sequence		Length	Mass (Da)
	Q492W6-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: C244FCF464675BF3	FASTA	337	37,952
	10 20 30 40 50 60 MIQIIYVASP ESQQIHVWKL DSIYGLLELI QVIYTHGQAQ PMAVHPNKRF LYVGIRPNFG 70 80 90 100 110 120 ITTYRIDQIG LLADHGTIGI FSSPTHLISD KKGAFLYCTS YRNNTVSVIP ISMSGMLLDS 130 140 150 160 170 180 PIQIIEGLLG CHSANIDKFK KLLWVPCLKE NAIRLFNINS FGMLTSYDPS IIKINVGSGP 190 200 210 220 230 240 RHMIFCDFDC YAYVINELTS TVDVIKYNNF QKIPSIVQTV SIIPKNISIN RCWAADIHIT 250 260 270 280 290 300 PNGRWLYCTD RSINIISCLE ISKKTKKLKF VGYQLTEEQP RGFAIDYQGK FLVVAGQKSN 310 320 330 CISLYKIDSD NGTLTMLSRY SSGKGPMWVS IITLNCK

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ40976.1.
RefSeq	YP_277851.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q492W6.
Genome annotation databases
GeneID	3562808.
GenomeReviews	Gene locus BPEN_351 in contig CP000016_GR.
KEGG	bpn:BPEN_351.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q492W6.
OMA	AYVINEL.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_351-MON.
Family and domain databases
HAMAP	MF_01605. [Tree]
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_BLOPB

Accession

Primary (citable) accession number: Q492W6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 12, 2007
Last sequence update:	September 13, 2005
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)