Reviewed, UniProtKB/Swiss-Prot Q492W5 (GPMA_BLOPB)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=PGAM
      Short name=BPG-dependent PGAM
      Short name=dPGM
    EC=5.4.2.1

Gene names

Name:	gpmA
Ordered Locus Names:	BPEN_352

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP MF_01039		PRO_0000229107
Sites
	Active site	11	1	Tele-phosphohistidine intermediate By similarity
	Active site	185	1	By similarity
	Site	62	1	Interaction with carboxyl group of phosphoglycerates By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q492W5-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 2AD8184F9C118E06	FASTA	232	26,998
	10 20 30 40 50 60 MHITKLVLIR HGESQWNKEN RFTGWVDVDL SEKGRSEAQC AGRILKKNGF FFNYGYTSVL 70 80 90 100 110 120 KRAIHTLWII LDQLDQAWLP IEKSWRLNER HYGALQGLNK DEAIKEYGYK TIQKWRRSFN 130 140 150 160 170 180 VIPPNICGGN NQFIATNDNR YANISTDELP SSESLELTLK RVIPYWNQSI IPHIKKGQTI 190 200 210 220 230 IIVAHGNSIR AIIKFLNHLN ESEIFQINVP TGVPLIYEFD KKANTVQHYY LK

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ40977.1.
RefSeq	YP_277852.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3562809.
GenomeReviews	Gene locus BPEN_352 in contig CP000016_GR.
KEGG	bpn:BPEN_352.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q492W5.
OMA	Q492W5. RVLPYWY.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_352-MON.
Family and domain databases
HAMAP	MF_01039. [Tree]
InterPro	IPR001345. PG/BPGM_mutase. IPR013078. PG_mutase. IPR005952. Phosphogly_mut1. [Graphical view]
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPMA_BLOPB

Accession

Primary (citable) accession number: Q492W5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)