Reviewed, UniProtKB/Swiss-Prot Q492S6 (AROA_BLOPB)

Names and origin

Protein names

Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferase
    EC=2.5.1.19
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthase
      Short name=EPSP synthase
      Short name=EPSPS

Gene names

Name:	aroA
Ordered Locus Names:	BPEN_393

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the EPSP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210		PRO_1000012411

Sequences

	Sequence		Length	Mass (Da)
	Q492S6-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: E943865E28250570	FASTA	432	47,427
	10 20 30 40 50 60 MNDFIKLAPI KKIQGTIHLP GSKSISNRAL LLAAQATGTT QLTNLLDSDD VRCMLDALRN 70 80 90 100 110 120 LGVSYCLSNN RKTCEINGIG GPIQSKNNNQ LILSLGNAGT VMRPLIAALS VQTQNIVLTG 130 140 150 160 170 180 HPRMKDRPIA HLVDALRQGG ARIEYMERNG YPPIRLYGGY YGGEIFIKGS ISSQFLSSVL 190 200 210 220 230 240 MMTPLAYRDT LIKVDGALVS RPYIDITLSL MKIFGINIQH DNYRVFYCKG NMAYQSPGDY 250 260 270 280 290 300 LVEGDASSAS YFLAASAIRG GTVRVIGVGR NSKQGDIYFA NILESMGAKI AWGDNYIECT 310 320 330 340 350 360 RGADLNAVDL DVNNIPDAAM TLAITALFSI NGPTILRNIY NWRVKESDRL AAMATELRKI 370 380 390 400 410 420 GAEIVEGYDY LQITPPFKIE SAYINTYDDH RIAMCFSLVA LSDVSIIINN PKCTDKTFPD 430 FFTQLSSISV LQ

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ41017.1.
RefSeq	YP_277892.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q492S6.
Genome annotation databases
GeneID	3562758.
GenomeReviews	Gene locus BPEN_393 in contig CP000016_GR.
KEGG	bpn:BPEN_393.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q492S6.
OMA	EIDTYND.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_393-MON.
Family and domain databases
HAMAP	MF_00210. [Tree]
InterPro	IPR016228. EPSP_synthase. IPR001986. EPSP_synthase_core. IPR006264. EPSP_synthase_subgroup. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
ProDom	PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01356. aroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROA_BLOPB

Accession

Primary (citable) accession number: Q492S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	November 3, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)