Reviewed, UniProtKB/Swiss-Prot Q492P3 (SYN_BLOPB)

Names and origin

Protein names

Recommended name:
    Asparaginyl-tRNA synthetase
    EC=6.1.1.22
Alternative name(s):
    Asparagine--tRNA ligase
      Short name=AsnRS

Gene names

Name:	asnS
Ordered Locus Names:	BPEN_433

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	470 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn). HAMAP MF_00534
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00534
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	asparaginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP aspartyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP asparagine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP aspartate-tRNA ligase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 470	470	Asparaginyl-tRNA synthetase HAMAP MF_00534		PRO_1000051381

Sequences

	Sequence		Length	Mass (Da)
	Q492P3-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 0237418B9E940552	FASTA	470	54,210
	10 20 30 40 50 60 MNVVSVVDIL SGHVSKNTEI TIQGWIRTRR DSKAKISFLD LYDGSCINSL QIIAYDKLHN 70 80 90 100 110 120 YKNEILRLTS GCSVIIVGII VKSIGIKQHV EVIAKNIKIL GWIEDPSTYP ITAKKHTMEY 130 140 150 160 170 180 LREVSHLRPR TNTIGAVARI RDTLSQAIHN FLHKQGFIWI PTPIITACDT EGSSKMFCVS 190 200 210 220 230 240 TSETQKILNN PNEKLHHTHD TTYDFFSKKA FLTVSGQLNA EAYACALSKV YTFGPTFRAE 250 260 270 280 290 300 YSNTNRHLAE FWMIEPEAAF MTLDDIIILA ESLLKNIIRI LLEKRSDDIK YLVDKINKNI 310 320 330 340 350 360 ITILENFSEI KFNHIEYTEA IKLLEICNRK FNNPIHWGTD LFSEHEKYLS EEYFKSPVII 370 380 390 400 410 420 KNFPKNIKAF YMRLNDDNKT VASMDILVPG IGEIIGGSQR EERLSKLDQR LQENCLTQEN 430 440 450 460 470 YWWYRDLRRY GTVPHSGFGL GFERLMIYVT GIKNIRDVIP FPRTSKNINF

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ41052.1.
RefSeq	YP_277928.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3562743.
GenomeReviews	Gene locus BPEN_433 in contig CP000016_GR.
KEGG	bpn:BPEN_433.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q492P3.
OMA	Q492P3. LQKKRHS.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_433-MON.
Family and domain databases
HAMAP	MF_00534. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004522. Asn-tRNA-synth_IIb. IPR002312. Asp-tRNA-synth_IIb. IPR012340. NA-bd_OB-fold. IPR004365. NA_bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
TIGRFAMs	TIGR00457. asnS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYN_BLOPB

Accession

Primary (citable) accession number: Q492P3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)