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Q492L0 (SYR_BLOPB) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BPEN_468
OrganismBlochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]
Taxonomic identifier291272 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 581581Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000241991

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q492L0 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 37AF0870CC47F172

FASTA58166,780
        10         20         30         40         50         60 
MNIQKFLLKK IHRALLAITN ESFFHLIQVQ QSTKRKFGNY QINGLIAISK KLNIPIEEFA 

        70         80         90        100        110        120 
KKFIQFINLN DVAHTIKIEK PGFINIFLNT KWISNQINNI FSASHLGITP ATPKTIVIDY 

       130        140        150        160        170        180 
SGPNVAKEMH VGHLRSTVIG DSIARVLSFL GHNVIRANHI GDWGTQFGML IAYIEKNAQT 

       190        200        210        220        230        240 
RFLLNKTIQL STLEHFYREA KKKYDIDPDF AELSRNYVLK LQKGDKHYRQ IWKYLVDISI 

       250        260        270        280        290        300 
LNNQDIYVRL NINLKKSDII GESFYNDMLP DIVSDLKNKG LAVTSNGATV VFLENYHNKL 

       310        320        330        340        350        360 
GTPFGVIIQK KDGAYLYSTT DIACIKYRCK VLHADRIIYY IDSRQKQHLI QAWEIADKAG 

       370        380        390        400        410        420 
YIEKSVLLEH HMCGMLLGKD GKPFKTRAGN ALKLKTLLDE ALERARCLIL SKNPNLKYTE 

       430        440        450        460        470        480 
INKLAHIISI GAIKYSELSK NRITDYIFDW NNMLNFEGNT APYVQYACTR IFAIFKRSKQ 

       490        500        510        520        530        540 
PNFQLKKNDI QLETEEEILL AICLLQFEEM IVAVSNQGAP HILCSYLYKL SVLFSSFYEN 

       550        560        570        580 
CPIIKAHNTH IKYSRLKLAL ITMRTLKTGL NLLGIKTVRY M 

« Hide

References

[1]"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects."
Degnan P.H., Lazarus A.B., Wernegreen J.J.
Genome Res. 15:1023-1033(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BPEN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000016 Genomic DNA. Translation: AAZ41087.1.
RefSeqYP_277963.1. NC_007292.1.

3D structure databases

ProteinModelPortalQ492L0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING291272.BPEN_468.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ41087; AAZ41087; BPEN_468.
GeneID3562964.
KEGGbpn:BPEN_468.
PATRIC31965854. VBICanBlo110049_0459.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycBPEN291272:GJ9N-816-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BLOPB
AccessionPrimary (citable) accession number: Q492L0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 13, 2005
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries