Reviewed, UniProtKB/Swiss-Prot Q492L0 (SYR_BLOPB)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BPEN_468

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	581 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 581	581	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000241991
Regions
	Motif	123 – 133	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q492L0-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 37AF0870CC47F172	FASTA	581	66,780
	10 20 30 40 50 60 MNIQKFLLKK IHRALLAITN ESFFHLIQVQ QSTKRKFGNY QINGLIAISK KLNIPIEEFA 70 80 90 100 110 120 KKFIQFINLN DVAHTIKIEK PGFINIFLNT KWISNQINNI FSASHLGITP ATPKTIVIDY 130 140 150 160 170 180 SGPNVAKEMH VGHLRSTVIG DSIARVLSFL GHNVIRANHI GDWGTQFGML IAYIEKNAQT 190 200 210 220 230 240 RFLLNKTIQL STLEHFYREA KKKYDIDPDF AELSRNYVLK LQKGDKHYRQ IWKYLVDISI 250 260 270 280 290 300 LNNQDIYVRL NINLKKSDII GESFYNDMLP DIVSDLKNKG LAVTSNGATV VFLENYHNKL 310 320 330 340 350 360 GTPFGVIIQK KDGAYLYSTT DIACIKYRCK VLHADRIIYY IDSRQKQHLI QAWEIADKAG 370 380 390 400 410 420 YIEKSVLLEH HMCGMLLGKD GKPFKTRAGN ALKLKTLLDE ALERARCLIL SKNPNLKYTE 430 440 450 460 470 480 INKLAHIISI GAIKYSELSK NRITDYIFDW NNMLNFEGNT APYVQYACTR IFAIFKRSKQ 490 500 510 520 530 540 PNFQLKKNDI QLETEEEILL AICLLQFEEM IVAVSNQGAP HILCSYLYKL SVLFSSFYEN 550 560 570 580 CPIIKAHNTH IKYSRLKLAL ITMRTLKTGL NLLGIKTVRY M

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000016 Genomic DNA. Translation: AAZ41087.1.
RefSeq	YP_277963.1.
3D structure databases
SMR	Q492L0. Positions 1-581.
ModBase	Search...
Protein-protein interaction databases
STRING	Q492L0.
Genome annotation databases
GeneID	3562964.
GenomeReviews	Gene locus BPEN_468 in contig CP000016_GR.
KEGG	bpn:BPEN_468.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HBG695395.
OMA	HMGFGTM.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_468-MONOMER.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM00836. DALR_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BLOPB

Accession

Primary (citable) accession number: Q492L0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	September 13, 2005
Last modified:	February 9, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)