Reviewed, UniProtKB/Swiss-Prot Q492G9 (AROC_BLOPB)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	BPEN_516

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 354	354	Chorismate synthase HAMAP MF_00300		PRO_0000256273

Sequences

	Sequence		Length	Mass (Da)
	Q492G9-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 7432F26034D5C32A	FASTA	354	38,719
	10 20 30 40 50 60 MAGNSIGQFF RVTTFGESHG SALGGIIDGV PPSLPLTEKD LQYDLDRRRP GSSRYTSQRS 70 80 90 100 110 120 ELDTVEILSG VFNGKTTGTS IGLLIKNTDH RPQDYEKIKN LYRPGHADYT YEKKYGFRDY 130 140 150 160 170 180 RGGGRSSARE TAVRVAAGAV AKKYLFNKKN IKIRGFLAQM GDVHCNLKDW RQVNNNPFFC 190 200 210 220 230 240 PDLEKLTALD TLINNLQKSG DSIGAKITVI AENIPIGLGE PVFDRLDADL AHALMSINAV 250 260 270 280 290 300 KGVEIGDGFS VITKRGSEHR DEMTLDGFNS NNSGGILGGI SNGQPIIMHI AIKPTSSITV 310 320 330 340 350 PGKTITRENE ETQVVTIGRH DPCIGIRVVP IAEAMVAIVV IDHLLRQRAQ CEKI

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ41130.1.
RefSeq	YP_278007.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q492G9.
Genome annotation databases
GeneID	3563141.
GenomeReviews	Gene locus BPEN_516 in contig CP000016_GR.
KEGG	bpn:BPEN_516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q492G9.
OMA	SRFTTQR.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_516-MON.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BLOPB

Accession

Primary (citable) accession number: Q492G9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	September 13, 2005
Last modified:	November 3, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)