Reviewed, UniProtKB/Swiss-Prot Q492C6 (PPNK_BLOPB)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23

Gene names

Name:	ppnK
Ordered Locus Names:	BPEN_565

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 297	297	Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361		PRO_0000229612

Sequences

	Sequence		Length	Mass (Da)
	Q492C6-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 38CFFD72729629FA	FASTA	297	33,048
	10 20 30 40 50 60 MTSSIFRTIG IIGYSRHPKA VHTYDILYHW LYSKGITVII EHHAASLLNV QKAVVGDLND 70 80 90 100 110 120 IGNYADLAIV IGGDGNMLRA ANILAQHDIK VIGINRGTLG FLTDLDPNSA LVELSDVLSG 130 140 150 160 170 180 HFINEKRFLL DVTVQRYNKL IRLGSAINEV ILHTNTIRDM IEFELYIDDN FIFSQRSDGL 190 200 210 220 230 240 IISTPTGSTA YALSAGGPIL SPTVDAILLV PICPHTLSSR PVVINSKSII CLKFSKVTSE 250 260 270 280 290 LKIGYDNQTP VLVCKEEEIF IKRSNHYLDL IHPNNYNYFK TLNIKLGWSQ NIAETKK

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ41175.1.
RefSeq	YP_278052.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q492C6.
Genome annotation databases
GeneID	3563130.
GenomeReviews	Gene locus BPEN_565 in contig CP000016_GR.
KEGG	bpn:BPEN_565.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q492C6.
OMA	MEQFRNI.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_565-MON.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK_BLOPB

Accession

Primary (citable) accession number: Q492C6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	September 13, 2005
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)