Q491Z7 (DAPF_BLOPB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	BPEN_600

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity HAMAP MF_00197.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 274	274	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000058540
Sites
	Active site	73	1	By similarity
	Active site	217	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q491Z7 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 40584B6CCB19BD22	FASTA	274	30,516
	10 20 30 40 50 60 MRFTKMNGLG NDFVIIDAVT QNIHLTSENI RYLSDRFYGV GFDQLLIVEP PYDPAIDFHC 70 80 90 100 110 120 RIYNSDGTEV NQCGNGMRCV AQFVCLKKLT NKRNIHISTR ANHIILSIMN DNRVSVNMGA 130 140 150 160 170 180 PIFDPKLIPF YISQYQKTYI LFLPTQIILC GVVSMGNPHC IILVEKIENI QVTSLGSALE 190 200 210 220 230 240 DHHCFPERVN VSFMQIINCN NIRLRVYERG VGETQACGTA ACAAVAVGIQ QGLLYESVNV 250 260 270 NLPGGTISVN WKGASNALYM TGSTSYVYDG YINL

References

[1]

"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BPEN.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000016 Genomic DNA. Translation: AAZ41205.1.
RefSeq	YP_278082.1. NC_007292.1.
3D structure databases
HSSP	HSSP built from PDB template 2GKE based on UniProtKB P44859.
ProteinModelPortal	Q491Z7.
SMR	Q491Z7. Positions 1-274.
ModBase	Search...
Protein-protein interaction databases
STRING	Q491Z7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3563073.
GenomeReviews	Gene locus BPEN_600 in contig CP000016_GR.
KEGG	bpn:BPEN_600.
PATRIC	31966137. VBICanBlo110049_0589.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0253.
HOGENOM	HBG399442.
OMA	FMTGPAT.
PhylomeDB	Q491Z7.
ProtClustDB	PRK00450.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_600-MONOMER.
Family and domain databases
HAMAP	MF_00197. DAP_epimerase. [Tree]
InterPro	IPR018510. DAP_epimerase_AS. IPR001653. DAP_epimerase_DapF. [Graphical view]
KO	K01778.
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_BLOPB

Accession

Primary (citable) accession number: Q491Z7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program