Q491X2 (COAD_BLOPB) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 43.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphopantetheine adenylyltransferase EC=2.7.7.3 Alternative name(s): Dephospho-CoA pyrophosphorylase Pantetheine-phosphate adenylyltransferase Short name=PPAT | ||||
| Gene names |
| ||||
| Organism | Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 291272 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia |
Protein attributes
| Sequence length | 171 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151 |
| Catalytic activity | ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151 |
| Pathway | Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151 |
| Subunit structure | Homohexamer By similarity. HAMAP MF_00151 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00151. |
| Sequence similarities | Belongs to the bacterial CoaD family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Coenzyme A biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | coenzyme A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW pantetheine-phosphate adenylyltransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 171 | 171 | Phosphopantetheine adenylyltransferase HAMAP MF_00151 | PRO_1000058159 | |||
Sequences
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References
| [1] | "Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BPEN. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000016 Genomic DNA. Translation: AAZ41232.1. |
| RefSeq | YP_278109.1. NC_007292.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1VLH based on UniProtKB Q9WZK0. |
| ProteinModelPortal | Q491X2. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q491X2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3562602. |
| GenomeReviews | Gene locus BPEN_634 in contig CP000016_GR. |
| KEGG | bpn:BPEN_634. |
| PATRIC | 31966207. VBICanBlo110049_0617. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0669. |
| HOGENOM | HBG288308. |
| OMA | AMSDFEY. |
| PhylomeDB | Q491X2. |
Enzyme and pathway databases | |
| BioCyc | CBLO291272:BPEN_634-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00151. PPAT_bact. [Tree] |
| InterPro | IPR004821. Cyt_trans-rel. IPR004820. Cytidylyltransf. IPR001980. LPS_biosynth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit. |
| KO | K00954. |
| Pfam | PF01467. CTP_transf_2. 1 hit. [Graphical view] |
| PRINTS | PR01020. LPSBIOSNTHSS. |
| TIGRFAMs | TIGR01510. CoaD_prev_kdtB. 1 hit. TIGR00125. Cyt_tran_rel. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | COAD_BLOPB | ||||||||
| Accession | Primary (citable) accession number: Q491X2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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