ID   G6PI_BLOPB              Reviewed;         551 AA.
AC   Q491V0;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Glucose-6-phosphate isomerase;
DE            Short=GPI;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase;
DE            Short=PGI;
DE   AltName: Full=Phosphohexose isomerase;
DE            Short=PHI;
GN   Name=pgi; OrderedLocusNames=BPEN_656;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   EMBL; CP000016; AAZ41254.1; -; Genomic_DNA.
DR   RefSeq; YP_278131.1; -.
DR   GeneID; 3562733; -.
DR   GenomeReviews; CP000016_GR; BPEN_656.
DR   KEGG; bpn:BPEN_656; -.
DR   HOGENOM; Q491V0; -.
DR   OMA; Q491V0; GPKIVSQ.
DR   BioCyc; CBLO291272:BPEN_656-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00473; -; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; G6P_Isomerase; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase.
FT   CHAIN         1    551       Glucose-6-phosphate isomerase.
FT                                /FTId=PRO_0000180602.
FT   ACT_SITE    356    356       Proton donor (By similarity).
FT   ACT_SITE    387    387       By similarity.
FT   ACT_SITE    515    515       By similarity.
SQ   SEQUENCE   551 AA;  62900 MW;  CF16606ACB3E39D9 CRC64;
     MKNINPNRTQ AWKHLKQHFD DMKSTSINDL FNQDKYRFAH FSKTFNNEIL VDYSKNLITN
     ETIIKLISLA IECDLIEAIS DMFHGEKINC SEDRAVLHIA LRNIKNTPIL VDGFNVMPQI
     NAVLNKMKQF CNRVIQGNWT GYTDKIITDI VNIGIGGSNL GPYMVTEALK PYRNHLNMHF
     VSNIDGTHIF ETLKNLNPEN TLFVIASKTF TTQETMTNAL SARNWFCKAT SDAQHISKHF
     IALSTNTIAV RKFGIDPSEN MFKFWDWVGG RYSLWSAIGL PIMLSVGVSN FELLLTGAHD
     MDIHFYSTPL HENLPVILAL IGIWYNNFFQ VETEAIFPYD QYMHRFTAYL QQVNMESNGK
     CVDRNGCPIT YQTGPIIWGE PGTNGQHSFY QLLHQGTKMV PCDFIAPAIS HNPISDHHEK
     LISNFFAQTK ALAFGNTHLT SMQKYIQSKK NYKHEQCIVP FKLCKGNNPS NSILVKKITP
     YTLGALIALY EHKIFTQGII FNIYTFDQWG VELGKQLADS ILPELKYESM ISKNHDSSTY
     GLIHCYKSWC G
//