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Q491V0 (G6PI_BLOPB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:BPEN_656
OrganismBlochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]
Taxonomic identifier291272 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180602

Sites

Active site3561Proton donor By similarity
Active site3871 By similarity
Active site5151 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q491V0 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: CF16606ACB3E39D9

FASTA55162,900
        10         20         30         40         50         60 
MKNINPNRTQ AWKHLKQHFD DMKSTSINDL FNQDKYRFAH FSKTFNNEIL VDYSKNLITN 

        70         80         90        100        110        120 
ETIIKLISLA IECDLIEAIS DMFHGEKINC SEDRAVLHIA LRNIKNTPIL VDGFNVMPQI 

       130        140        150        160        170        180 
NAVLNKMKQF CNRVIQGNWT GYTDKIITDI VNIGIGGSNL GPYMVTEALK PYRNHLNMHF 

       190        200        210        220        230        240 
VSNIDGTHIF ETLKNLNPEN TLFVIASKTF TTQETMTNAL SARNWFCKAT SDAQHISKHF 

       250        260        270        280        290        300 
IALSTNTIAV RKFGIDPSEN MFKFWDWVGG RYSLWSAIGL PIMLSVGVSN FELLLTGAHD 

       310        320        330        340        350        360 
MDIHFYSTPL HENLPVILAL IGIWYNNFFQ VETEAIFPYD QYMHRFTAYL QQVNMESNGK 

       370        380        390        400        410        420 
CVDRNGCPIT YQTGPIIWGE PGTNGQHSFY QLLHQGTKMV PCDFIAPAIS HNPISDHHEK 

       430        440        450        460        470        480 
LISNFFAQTK ALAFGNTHLT SMQKYIQSKK NYKHEQCIVP FKLCKGNNPS NSILVKKITP 

       490        500        510        520        530        540 
YTLGALIALY EHKIFTQGII FNIYTFDQWG VELGKQLADS ILPELKYESM ISKNHDSSTY 

       550 
GLIHCYKSWC G 

« Hide

References

[1]"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects."
Degnan P.H., Lazarus A.B., Wernegreen J.J.
Genome Res. 15:1023-1033(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BPEN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000016 Genomic DNA. Translation: AAZ41254.1.
RefSeqYP_278131.1. NC_007292.1.

3D structure databases

ProteinModelPortalQ491V0.
SMRQ491V0. Positions 7-549.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING291272.BPEN_656.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ41254; AAZ41254; BPEN_656.
GeneID3562733.
KEGGbpn:BPEN_656.
PATRIC31966251. VBICanBlo110049_0639.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_BLOPB
AccessionPrimary (citable) accession number: Q491V0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: September 13, 2005
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways