Reviewed, UniProtKB/Swiss-Prot Q491V0 (G6PI_BLOPB)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	BPEN_656

Organism

Blochmannia pennsylvanicus (strain BPEN) [Complete proteome] [HAMAP]

Taxonomic identifier

291272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 551	551	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000180602
Sites
	Active site	356	1	Proton donor By similarity
	Active site	387	1	By similarity
	Active site	515	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q491V0-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: CF16606ACB3E39D9	FASTA	551	62,900
	10 20 30 40 50 60 MKNINPNRTQ AWKHLKQHFD DMKSTSINDL FNQDKYRFAH FSKTFNNEIL VDYSKNLITN 70 80 90 100 110 120 ETIIKLISLA IECDLIEAIS DMFHGEKINC SEDRAVLHIA LRNIKNTPIL VDGFNVMPQI 130 140 150 160 170 180 NAVLNKMKQF CNRVIQGNWT GYTDKIITDI VNIGIGGSNL GPYMVTEALK PYRNHLNMHF 190 200 210 220 230 240 VSNIDGTHIF ETLKNLNPEN TLFVIASKTF TTQETMTNAL SARNWFCKAT SDAQHISKHF 250 260 270 280 290 300 IALSTNTIAV RKFGIDPSEN MFKFWDWVGG RYSLWSAIGL PIMLSVGVSN FELLLTGAHD 310 320 330 340 350 360 MDIHFYSTPL HENLPVILAL IGIWYNNFFQ VETEAIFPYD QYMHRFTAYL QQVNMESNGK 370 380 390 400 410 420 CVDRNGCPIT YQTGPIIWGE PGTNGQHSFY QLLHQGTKMV PCDFIAPAIS HNPISDHHEK 430 440 450 460 470 480 LISNFFAQTK ALAFGNTHLT SMQKYIQSKK NYKHEQCIVP FKLCKGNNPS NSILVKKITP 490 500 510 520 530 540 YTLGALIALY EHKIFTQGII FNIYTFDQWG VELGKQLADS ILPELKYESM ISKNHDSSTY 550 GLIHCYKSWC G

References

[1]	"Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects." Degnan P.H., Lazarus A.B., Wernegreen J.J. Genome Res. 15:1023-1033(2005) [PubMed: 16077009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000016 Genomic DNA. Translation: AAZ41254.1.
RefSeq	YP_278131.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3562733.
GenomeReviews	Gene locus BPEN_656 in contig CP000016_GR.
KEGG	bpn:BPEN_656.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q491V0.
OMA	Q491V0. GPKIVSQ.
Enzyme and pathway databases
BioCyc	CBLO291272:BPEN_656-MON.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_BLOPB

Accession

Primary (citable) accession number: Q491V0

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)