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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Blochmannia pennsylvanicus (strain BPEN)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei356Proton donorUniRule annotation1
Active sitei387UniRule annotation1
Active sitei515UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCBLO291272:G1G3Y-657-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:BPEN_656
OrganismiBlochmannia pennsylvanicus (strain BPEN)
Taxonomic identifieri291272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia
Proteomesi
  • UP000007794 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806021 – 551Glucose-6-phosphate isomeraseAdd BLAST551

Proteomic databases

PRIDEiQ491V0

Interactioni

Protein-protein interaction databases

STRINGi291272.BPEN_656

Structurei

3D structure databases

ProteinModelPortaliQ491V0
SMRiQ491V0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261371
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q491V0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNINPNRTQ AWKHLKQHFD DMKSTSINDL FNQDKYRFAH FSKTFNNEIL
60 70 80 90 100
VDYSKNLITN ETIIKLISLA IECDLIEAIS DMFHGEKINC SEDRAVLHIA
110 120 130 140 150
LRNIKNTPIL VDGFNVMPQI NAVLNKMKQF CNRVIQGNWT GYTDKIITDI
160 170 180 190 200
VNIGIGGSNL GPYMVTEALK PYRNHLNMHF VSNIDGTHIF ETLKNLNPEN
210 220 230 240 250
TLFVIASKTF TTQETMTNAL SARNWFCKAT SDAQHISKHF IALSTNTIAV
260 270 280 290 300
RKFGIDPSEN MFKFWDWVGG RYSLWSAIGL PIMLSVGVSN FELLLTGAHD
310 320 330 340 350
MDIHFYSTPL HENLPVILAL IGIWYNNFFQ VETEAIFPYD QYMHRFTAYL
360 370 380 390 400
QQVNMESNGK CVDRNGCPIT YQTGPIIWGE PGTNGQHSFY QLLHQGTKMV
410 420 430 440 450
PCDFIAPAIS HNPISDHHEK LISNFFAQTK ALAFGNTHLT SMQKYIQSKK
460 470 480 490 500
NYKHEQCIVP FKLCKGNNPS NSILVKKITP YTLGALIALY EHKIFTQGII
510 520 530 540 550
FNIYTFDQWG VELGKQLADS ILPELKYESM ISKNHDSSTY GLIHCYKSWC

G
Length:551
Mass (Da):62,900
Last modified:September 13, 2005 - v1
Checksum:iCF16606ACB3E39D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000016 Genomic DNA Translation: AAZ41254.1
RefSeqiWP_011283165.1, NC_007292.1

Genome annotation databases

EnsemblBacteriaiAAZ41254; AAZ41254; BPEN_656
KEGGibpn:BPEN_656

Similar proteinsi

Entry informationi

Entry nameiG6PI_BLOPB
AccessioniPrimary (citable) accession number: Q491V0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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