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Protein

Polyferredoxin protein MvhB

Gene

mvhB

Organism
Methanothermus fervidus
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterCuratedNote: Binds 10 [4Fe-4S] clusters.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi9 – 91Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi12 – 121Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi15 – 151Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi19 – 191Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi75 – 751Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi78 – 781Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi81 – 811Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi85 – 851Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi107 – 1071Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi110 – 1101Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi113 – 1131Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi117 – 1171Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi146 – 1461Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi149 – 1491Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi152 – 1521Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi156 – 1561Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi177 – 1771Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi180 – 1801Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi183 – 1831Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi187 – 1871Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi216 – 2161Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi219 – 2191Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi222 – 2221Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi226 – 2261Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi245 – 2451Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi248 – 2481Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi251 – 2511Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi255 – 2551Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi284 – 2841Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi287 – 2871Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi290 – 2901Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi294 – 2941Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi324 – 3241Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi327 – 3271Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi330 – 3301Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi334 – 3341Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi365 – 3651Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi368 – 3681Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi371 – 3711Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi375 – 3751Iron-sulfur (4Fe-4S)Sequence analysis

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyferredoxin protein MvhB
Gene namesi
Name:mvhB
OrganismiMethanothermus fervidus
Taxonomic identifieri2180 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanothermaceaeMethanothermus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Polyferredoxin protein MvhBPRO_0000159142Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi523846.Mfer_0730.

Structurei

3D structure databases

ProteinModelPortaliQ49180.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 29284Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini30 – 57284Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini66 – 95304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
BLAST
Domaini96 – 127324Fe-4S ferredoxin-type 4PROSITE-ProRule annotationAdd
BLAST
Domaini138 – 166294Fe-4S ferredoxin-type 5PROSITE-ProRule annotationAdd
BLAST
Domaini168 – 197304Fe-4S ferredoxin-type 6PROSITE-ProRule annotationAdd
BLAST
Domaini207 – 236304Fe-4S ferredoxin-type 7PROSITE-ProRule annotationAdd
BLAST
Domaini237 – 265294Fe-4S ferredoxin-type 8PROSITE-ProRule annotationAdd
BLAST
Domaini275 – 304304Fe-4S ferredoxin-type 9PROSITE-ProRule annotationAdd
BLAST
Domaini311 – 344344Fe-4S ferredoxin-type 10PROSITE-ProRule annotationAdd
BLAST
Domaini356 – 385304Fe-4S ferredoxin-type 11PROSITE-ProRule annotationAdd
BLAST
Domaini386 – 412274Fe-4S ferredoxin-type 12PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 12 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG02181. Archaea.
COG1145. LUCA.

Family and domain databases

InterProiIPR001080. 3Fe4S_ferredoxin.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF00037. Fer4. 1 hit.
PF12838. Fer4_7. 3 hits.
PF13187. Fer4_9. 1 hit.
[Graphical view]
PRINTSiPR00352. 3FE4SFRDOXIN.
PROSITEiPS00198. 4FE4S_FER_1. 10 hits.
PS51379. 4FE4S_FER_2. 12 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49180-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVINKEDCI RCGACQGVCP TGAISVKPED VIYCDMCGGE PKCVEACPND
60 70 80 90 100
ALRHEDITLE GGIKKKKITY SPEKCDKCGE CVKVCPPGIL KLVNDGKASR
110 120 130 140 150
VPLEGFCVLC QQCVNVCPIE VIGIEGVKEP ARVEIKIDKP IYIVDCVGCG
160 170 180 190 200
LCVPECPVNA ITLPKYGESI EIDEEKCIKC GICAQTCPWN SVYISGKKPQ
210 220 230 240 250
KSSRTIENFT LDKEECIGCN TCVEICPGGF IEPKSDLTVS LPEICPACGL
260 270 280 290 300
CEKLCPTDAI ELEVKLGPAK PVTEEGIVYN DENCKFCGRC ALNCPNEAIR
310 320 330 340 350
VVSPKGRVFP GLKKVDEKES YTICTTCGAC TTVCPTGALK LVEVSKKVNG
360 370 380 390 400
ETVKRNRIQY NPSLCDKCGN CVDVCPYGIL KLTDDEKLPV KGFCILCEKC
410
IDACRFNALL IK
Length:412
Mass (Da):44,642
Last modified:November 1, 1996 - v1
Checksum:i886F2F9CA9EDFCF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34016 Genomic DNA. Translation: AAA72833.1.
PIRiC37777.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34016 Genomic DNA. Translation: AAA72833.1.
PIRiC37777.

3D structure databases

ProteinModelPortaliQ49180.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi523846.Mfer_0730.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiarCOG02181. Archaea.
COG1145. LUCA.

Family and domain databases

InterProiIPR001080. 3Fe4S_ferredoxin.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF00037. Fer4. 1 hit.
PF12838. Fer4_7. 3 hits.
PF13187. Fer4_9. 1 hit.
[Graphical view]
PRINTSiPR00352. 3FE4SFRDOXIN.
PROSITEiPS00198. 4FE4S_FER_1. 10 hits.
PS51379. 4FE4S_FER_2. 12 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMVHB_METFE
AccessioniPrimary (citable) accession number: Q49180
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.