Q48ZB1 (Q48ZB1_STRP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL AAZ51307.1
EC=1.5.1.3 EMBL AAZ51307.1

Gene names

Name:	dyr EMBL AAZ51307.1
Ordered Locus Names:	M5005_Spy0689

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL AAZ51307.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q48ZB1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: D3855A2479A6D739	FASTA	165	19,358
	10 20 30 40 50 60 MTKEIIAIWA EDEAGLIGVA GKLPWYLPKE LEHFKKTTLH QAILMGRVTF EGMNCKRLPQ 70 80 90 100 110 120 RQTLVMTRNR DYQVDEVLTM TSIEKVLEWY HAQDKTLYII GGNKVLEAFN GYFDRVIKTV 130 140 150 160 IHHRFKGDTY RPNLDFSHFT QESQTFYARD AKNPYDFTVT ALKHK

References

[1]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed: 16088826] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000017 Genomic DNA. Translation: AAZ51307.1.
RefSeq	YP_282052.1. NC_007297.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000028705; EBSTRP00000027723; EBSTRG00000028705.
GeneID	3572240.
GenomeReviews	Gene locus M5005_Spy0689 in contig CP000017_GR.
KEGG	spz:M5005_Spy_0689.
PATRIC	19740133. VBIStrPyo7871_0718.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027355.
HOGENOM	HBG665708.
ProtClustDB	CLSK797453.
Enzyme and pathway databases
BioCyc	SPYO293653:M5005_SPY0689-MONOMER.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q48ZB1_STRP1

Accession

Primary (citable) accession number: Q48ZB1

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)