Q48XK3 (Q48XK3_STRP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta-galactosidase EMBL AAZ51922.1
EC=3.2.1.23 EMBL AAZ51922.1

Gene names

Name:	lacZ EMBL AAZ51922.1
Ordered Locus Names:	M5005_Spy1304

Organism

Streptococcus pyogenes serotype M1 [Complete proteome] [HAMAP]

Taxonomic identifier

301447 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pyogenes

Protein attributes

Sequence length	1138 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Glycosidase EMBL AAZ51922.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	beta-galactosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q48XK3 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 91267821EA5A0D51	FASTA	1,138	128,498
	10 20 30 40 50 60 MTPDSKEQTV TGYQYHYIDQ EGRKQPFNQG WRFLMADVAC AQDPSFDDSN WQVIHLPHDF 70 80 90 100 110 120 SLTQPYTRNG EAESAYKLGG VGWYRHYLVL DEVLAGCHVA ITFEGSYMET EIYVNGQFIG 130 140 150 160 170 180 KHLNGYQEFT YDISDVVTFG AENLLAVRVE NKVPSSRWYS GSGLYREVSL SVLPQLHFVA 190 200 210 220 230 240 DQVAMTLADT AVQEKGQQKV DLRFALNQSI QTCHYQLSLC LWEQSHCSKD KKLLYQETEV 250 260 270 280 290 300 PLADLAFQRQ YGLTLSLEEL QLWSPDNPHL YDLELTLYYQ GQVIDCFCLE TGFRQLTFMA 310 320 330 340 350 360 NQGLFVNGRA VKLKGVCLHH DQGGLGACAY EDALARQLVL LKDMGANTIR STHNPSSPKL 370 380 390 400 410 420 RQLANRLGFF VIEEAFDTWT YAKNGNVNDF SNYFHQTIGT ENANYLQRVR SPETSWAQYS 430 440 450 460 470 480 IEAMVWSAKN DPSVLMWSIG NELMEGFSAD VSHYPELTRQ MCQWITAIDT SRPITFGDNK 490 500 510 520 530 540 LKEADFCWHE EVSQMATLLS QLDHPQGLIG LNYADGKDYD RLHEEHSDWL LYGSETVSAI 550 560 570 580 590 600 TSRAYYKETK KVLDSGYHLT SYDHAKVDWG AFASQAWYDT ITRDFVAGEC VWTGFDYLGE 610 620 630 640 650 660 PTPWNKIDSG VVGLWPSPKN AYFGILDTAG FPKDSYYFYQ SQWAQGQTTL HLLPVWQKDQ 670 680 690 700 710 720 LCFDEQGLVE VVVYSNAASV QLMFEDEQGN LTDYGRKAFH TYSTPTGHTY QLYQGADAAK 730 740 750 760 770 780 NPHENLYLTW RVPYQKGLLR AVAYDISGKS IPKTSGRSQV RTYGSVAKLS WKAFEAPIDA 790 800 810 820 830 840 PWELLYLDLS LLDSRGELVS HAQDWLQVQV EGPARLLALD NGNPTDHTPY QEPLRQAYGG 850 860 870 880 890 900 KLLAILALTG EAGHIKVTAK ASQQLSSVFQ TQVACRAPKE HLVTLPLEKY QFKKSRLTSQ 910 920 930 940 950 960 QEIGQSCLKT TQFLSVLENK DTQQKAGKAS TPHILITSYQ HYLSLPLQVC SQAFDFKKGD 970 980 990 1000 1010 1020 DIFLPQWLQV KDAQGSLVKK AFSMTWYLKE KIFAKPILVT GYVSCFGQSI PVEARLNLAQ 1030 1040 1050 1060 1070 1080 ASKRRHQDLS LVAKQSLAAS QKRLTYCYQY DTVQAIGAIS LQNHTGTSLS VSVAISYGSQ 1090 1100 1110 1120 1130 SSIKQETLML ADSHLSQLEE VIFFDDILTV LYLAVTLEVI EGPDLTEDSI QIGLWDLA

References

[1]

"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events." Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M. J. Infect. Dis. 192:771-782(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-947 / MGAS5005 / Serotype M1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000017 Genomic DNA. Translation: AAZ51922.1.
RefSeq	YP_282667.1. NC_007297.1.
3D structure databases
ProteinModelPortal	Q48XK3.
ModBase	Search...
Protein-protein interaction databases
STRING	293653.M5005_Spy_1304.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAZ51922; AAZ51922; M5005_Spy1304.
GeneID	3571618.
KEGG	spz:M5005_Spy_1304.
PATRIC	19741399. VBIStrPyo7871_1347.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01190.
ProtClustDB	CLSK698781.
Family and domain databases
Gene3D	2.60.40.320. 1 hit. 3.20.20.80. 1 hit.
InterPro	IPR008979. Galactose-bd-like. IPR006101. Glyco_hydro_2. IPR013812. Glyco_hydro_2/20_Ig-like. IPR006102. Glyco_hydro_2_Ig-like. IPR006104. Glyco_hydro_2_N. IPR006103. Glyco_hydro_2_TIM. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Pfam	PF00703. Glyco_hydro_2. 1 hit. PF02836. Glyco_hydro_2_C. 1 hit. PF02837. Glyco_hydro_2_N. 1 hit. [Graphical view]
PRINTS	PR00132. GLHYDRLASE2.
SUPFAM	SSF49785. Gal_bind_like. 1 hit. SSF49303. Glyco_hydro_2Ig. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q48XK3_STRP1

Accession

Primary (citable) accession number: Q48XK3

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)