Q48TV7 (Q48TV7_STRPM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL AAX71849.1
EC=4.2.2.1 EMBL AAX71849.1

Gene names

Name:	hylA EMBL AAX71849.1
Ordered Locus Names:	M28_Spy0736

Organism

Streptococcus pyogenes serotype M28 [Complete proteome] [HAMAP]

Taxonomic identifier

319700 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	828 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL AAX71849.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q48TV7 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: F69FB8C2571356C5	FASTA	828	95,423
	10 20 30 40 50 60 MVYFYLVNQF TFIISFLYRR NLSVNTYFCT HHKQLLLYSN LFLSFAMMGQ GTAIYADTLT 70 80 90 100 110 120 SNSEPNNTYF QTQMLTTTDS EKKVVQPQQK DYYTELLDQW NSIIAGNDAY DKTNPDMVTF 130 140 150 160 170 180 HNKAEKDAQN IIKSYQGPDH ENRTYLWEHA KDYSASANIT KTYRNIEKIA KQITNPESCY 190 200 210 220 230 240 YQDSKAIAIV KDGMAFMYEH AYNLDRENHQ TTGKENKENW WVYEIGTPRA INNTLSLMYP 250 260 270 280 290 300 YFTQEEILKY TAPIEKFVPD PTRFRVRAAN FSPFEANSGN LIDMGRVKLI SGILRKDDLE 310 320 330 340 350 360 ISDTIKAIEK VFTLVDEGNG FYQDGSLIDH VVTNAQSPLY KKGIAYTGAY GNVLIDGLSQ 370 380 390 400 410 420 LIPIIQKTKS SIEADKMATI YHWINHSFFP IIVRGEMMDM TRGRSISRFN AQSHVAGIEA 430 440 450 460 470 480 LRAILRIADM SEEPHRLALK TRIKTLVTQG NAFYNVYDNL KTYHDIKLMK ELLSDTSVPV 490 500 510 520 530 540 QKLDSYVASF NSMDKLALYN NKHDFAFGLS MFSNRTQNYE AMNNENLHGW FTSDGMFYLY 550 560 570 580 590 600 NNDLGHYSEN YWATVNPYRL PGTTETEQKP LEGTPENIKT NYQQVGMTSL SDDAFVASKK 610 620 630 640 650 660 LNNTSALAAM TFTNWNKSLT LNKGWFILGN KIIFVGSNIK NQSSHKAYTT IEQRKENQKH 670 680 690 700 710 720 PYHAYVNNQP VDLNNQLVDF TNTKSIFLES DDSAQNIGYY FFKPTTLSIS KALQTGKWQN 730 740 750 760 770 780 IKADDKSPEA IKEVSNTFIT IMQNHTQDGD RYAYMMLPNM TRQEFETYIS KLDIDLLENN 790 800 810 820 DKLAAVYDHD SQQMHVIHYE KKATMFSNHN LSHQGFYSFP HPVKQNQQ

References

[1]

"Genome sequence of a serotype M28 strain of group A Streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity." Green N.M., Zhang S., Porcella S.F., Nagiec M.J., Barbian K.D., Beres S.B., Lefebvre R.B., Musser J.M. J. Infect. Dis. 192:760-770(2005) [PubMed: 16088825] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: MGAS6180 EMBL AAX71849.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000056 Genomic DNA. Translation: AAX71849.1.
RefSeq	YP_280204.1. NC_007296.1.
3D structure databases
ProteinModelPortal	Q48TV7.
SMR	Q48TV7. Positions 90-803.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000032323; EBSTRP00000031155; EBSTRG00000032323.
GeneID	3573504.
GenomeReviews	Gene locus M28_Spy0736 in contig CP000056_GR.
KEGG	spb:M28_Spy0736.
PATRIC	19744248. VBIStrPyo35950_0755.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027679.
HOGENOM	HBG698564.
OMA	TKTYRNI.
ProtClustDB	CLSK442844.
Enzyme and pathway databases
BioCyc	SPYO319701:M28_SPY0736-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q48TV7_STRPM

Accession

Primary (citable) accession number: Q48TV7

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)