Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Aspartate aminotransferase

Gene

M28_Spy1502

Organism
Streptococcus pyogenes serotype M28 (strain MGAS6180)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Enzyme and pathway databases

BioCyciSPYO319701:GHAD-1568-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Aspartate aminotransferaseImported (EC:2.6.1.1Imported)
Gene namesi
Ordered Locus Names:M28_Spy1502Imported
OrganismiStreptococcus pyogenes serotype M28 (strain MGAS6180)Imported
Taxonomic identifieri319701 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000009292 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi319701.M28_Spy1502.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000223042.
KOiK14260.
OMAiQRNRTWE.
OrthoDBiEOG6X9MJ6.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q48RP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVYNMEYEVY ETMKIIEKSS KLEHVAYDIR GPVLDEANRM IASGEKILRL
60 70 80 90 100
NTGNPAAFGF EAPDEVIRDL IVNARLSEGY SDSKGIFSAR KAIMQYCQLK
110 120 130 140 150
GFPDVDIEDI YLGNGVSELI SISLQALLDN GDEVLVPMPD YPLWTACVSL
160 170 180 190 200
GGGKAVHYLC DEEAGWYPDI ADIKSKITSR TKAIVVINPN NPTGALYPKE
210 220 230 240 250
ILEDIVALAR EHQLIIFADE IYDRLVMDGK EHIAIASLAP DVFCVSMNGL
260 270 280 290 300
SKSHRIAGFR VGWMVLSGPK DHVKGYIEGL NMLANMRLCS NVLAQQVVQT
310 320 330 340 350
SLGGHQSVDA LLLPGGRIFE QRNFIYEAIN AIPGLSAVKP EAGLYLFPKI
360 370 380 390 400
DRQMYRIDDD EEFVLQLLKQ EKVMLVHGRG FNWKDPDHFR IVYLPSVEEL
410
EDVQEKITRV LYQYRR
Length:416
Mass (Da):46,776
Last modified:September 13, 2005 - v1
Checksum:i5FAFA06FD060EA73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000056 Genomic DNA. Translation: AAX72612.1.
RefSeqiYP_280967.2. NC_007296.1.

Genome annotation databases

EnsemblBacteriaiAAX72612; AAX72612; M28_Spy1502.
GeneIDi3574223.
KEGGispb:M28_Spy1502.
PATRICi19745849. VBIStrPyo35950_1542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000056 Genomic DNA. Translation: AAX72612.1.
RefSeqiYP_280967.2. NC_007296.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi319701.M28_Spy1502.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX72612; AAX72612; M28_Spy1502.
GeneIDi3574223.
KEGGispb:M28_Spy1502.
PATRICi19745849. VBIStrPyo35950_1542.

Phylogenomic databases

HOGENOMiHOG000223042.
KOiK14260.
OMAiQRNRTWE.
OrthoDBiEOG6X9MJ6.

Enzyme and pathway databases

BioCyciSPYO319701:GHAD-1568-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of a serotype M28 strain of group A Streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity."
    Green N.M., Zhang S., Porcella S.F., Nagiec M.J., Barbian K.D., Beres S.B., Lefebvre R.B., Musser J.M.
    J. Infect. Dis. 192:760-770(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MGAS6180Imported.

Entry informationi

Entry nameiQ48RP8_STRPM
AccessioniPrimary (citable) accession number: Q48RP8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: March 4, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.