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Q48P88 (Q48P88_PSE14) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. HAMAP-Rule MF_00162

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00162

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. HAMAP-Rule MF_00162

Sequence similarities

Belongs to the prokaryotic GSH synthase family. HAMAP-Rule MF_00162

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00162

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain125 – 311187ATP-grasp By similarity HAMAP-Rule MF_00162
Nucleotide binding152 – 20857ATP By similarity HAMAP-Rule MF_00162

Sites

Metal binding2821Magnesium or manganese By similarity HAMAP-Rule MF_00162
Metal binding2841Magnesium or manganese By similarity HAMAP-Rule MF_00162

Sequences

Sequence LengthMass (Da)Tools
Q48P88 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 8C35B117D4BFAF96

FASTA31935,280
        10         20         30         40         50         60 
MSVRLGIVMD PIERISYKKD SSLAMLLAAQ ERGWSLFYME QKDLYQDAGQ ARARMKPLKV 

        70         80         90        100        110        120 
FADPAKWFEF EAEVDAGLDD LDVILMRKDL PFDMEFVYAT YLLEQAERAG VLVVNKPQSL 

       130        140        150        160        170        180 
RDCNEKLFAT LFPQCTPPTL VSRRADIIRE FAEKHGDVIL KPLDGMGGAS IFRHRAGDPN 

       190        200        210        220        230        240 
LSVILETLTA HGTQQIMAQG YLPAIKDGDK RILMVDGEPV PYCLARIPAA GETRGNLAAG 

       250        260        270        280        290        300 
GRGEARPLSD KDRWIAEQIG PTLREKGLLF VGLDVIGEHL TEINVTSPGG IREIDNAFGT 

       310 
NIGGLLIDAI DKKLQARRG 

« Hide

References

[1]"Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition."
Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Crabtree J., Creasy T., Davidsen T.M., Haft D.H. expand/collapse author list , Zafar N., Zhou L., Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O., Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D., Mansfield J.W., Collmer A., Buell R.
J. Bacteriol. 187:6488-6498(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1448A / Race 6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000058 Genomic DNA. Translation: AAZ34205.1.
RefSeqYP_272781.1. NC_005773.3.

3D structure databases

ProteinModelPortalQ48P88.
SMRQ48P88. Positions 3-315.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264730.PSPPH_0478.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ34205; AAZ34205; PSPPH_0478.
GeneID3556749.
KEGGpsp:PSPPH_0478.
PATRIC19969988. VBIPseSyr78478_0519.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0189.
HOGENOMHOG000265022.
KOK01920.
OMAXRRTSAS.
OrthoDBEOG6WMHWB.

Enzyme and pathway databases

BioCycPSAV264730:GKDE-479-MONOMER.
UniPathwayUPA00142; UER00210.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00162. GSH_S.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR006284. Glut_synth_pro.
IPR004218. GSHS_ATP-bd.
IPR004215. GSHS_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PfamPF02955. GSH-S_ATP. 1 hit.
PF02951. GSH-S_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01380. glut_syn. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ48P88_PSE14
AccessionPrimary (citable) accession number: Q48P88
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)