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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) (Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase, Transferase
Biological processPyridine nucleotide biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
Ordered Locus Names:PSPPH_0588
OrganismiPseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) (Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6))
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000551 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000250041 – 407Nicotinate phosphoribosyltransferaseAdd BLAST407

Proteomic databases

PRIDEiQ48NY1

Interactioni

Protein-protein interaction databases

STRINGi264730.PSPPH_0588

Structurei

3D structure databases

ProteinModelPortaliQ48NY1
SMRiQ48NY1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RH7 Bacteria
COG1488 LUCA
HOGENOMiHOG000284928
KOiK00763
OMAiKLTMQCA

Family and domain databases

CDDicd01401 PncB_like, 1 hit
HAMAPiMF_00570 NAPRTase, 1 hit
InterProiView protein in InterPro
IPR006406 Nic_PRibTrfase
IPR007229 Nic_PRibTrfase-Fam
IPR036068 Nicotinate_pribotase_like_C
PANTHERiPTHR11098 PTHR11098, 1 hit
PfamiView protein in Pfam
PF04095 NAPRTase, 1 hit
PIRSFiPIRSF000484 NAPRT, 1 hit
SUPFAMiSSF51690 SSF51690, 1 hit
TIGRFAMsiTIGR01514 NAPRTase, 1 hit

Sequencei

Sequence statusi: Complete.

Q48NY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESAFSNRI VQSLLDTDFY KLTMMQAVLH NYPNVDVEWE FRCRNGEDLR
60 70 80 90 100
PYLDEIRHQI ELLCELSLSP EHLAFLERIT FIKPDFLRFL GLFRFNTRYV
110 120 130 140 150
KTSIENDELC IRLHGPWLHV ILFEVPLLAI VSEVRNRHRY PDTLLSQARD
160 170 180 190 200
RLYDKFEWLT THATADELAE LKVADFGTRR RFSYRVQEEM LGVLKNDFPG
210 220 230 240 250
QFVGTSNVHL ARQLDLKPLG TMAHEWIMAH QQLGPRLIDS QIAALDCWVR
260 270 280 290 300
EYRGLLGIAL TDCITTDAFL NDFDLYFAKL FDGLRHDSGD PVKWAEKCIS
310 320 330 340 350
HYQKLGIDPM SKTLVFSDGL NLPKALDIFR ALRGRINVSF GIGTNLTADI
360 370 380 390 400
PGIAPMNMVL KMTACAGQAV AKISDEPGKT QCKDPNFVAY LRHVFKVPDL

PSPEKPA
Length:407
Mass (Da):46,662
Last modified:September 13, 2005 - v1
Checksum:i52B4F689E37FDED3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA Translation: AAZ35602.1
RefSeqiWP_002551841.1, NC_005773.3

Genome annotation databases

EnsemblBacteriaiAAZ35602; AAZ35602; PSPPH_0588
KEGGipsp:PSPPH_0588

Similar proteinsi

Entry informationi

Entry nameiPNCB_PSE14
AccessioniPrimary (citable) accession number: Q48NY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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