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Q48MN1 (Q48MN1_PSE14) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 1 HAMAP MF_00223

EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I 1 HAMAP MF_00223
Gene names
Name:folE1 HAMAP MF_00223
Ordered Locus Names:PSPPH_1071
OrganismPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) [Complete proteome] [HAMAP] EMBL AAZ34804.1
Taxonomic identifier264730 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonasPseudomonas syringae pv. savastanoi

Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding751Zinc By similarity HAMAP MF_00223
Metal binding781Zinc By similarity HAMAP MF_00223
Metal binding1461Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
Q48MN1 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 933E197DA545D62B

FASTA18720,798
        10         20         30         40         50         60 
MSSSLPQHYR DILLGLGEDP DREGLLDTPK RASKAMQYLC HGYTQSVDEI VNGALFASDN 

        70         80         90        100        110        120 
DEMVIVQNIE LYSLCEHHLL PFIGKAHVAY IPTGKVLGLS KIARIVDMFA RRLQIQENLT 

       130        140        150        160        170        180 
KQIADAIQQV TGAAGVAVVI EAKHMCMMMR GVEKQNSTMN TSVMLGAFRD SSTTRMEFLQ 


LIGRSRQ 

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References

[1]"Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition."
Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Crabtree J., Creasy T., Davidsen T.M., Haft D.H. expand/collapse author list , Zafar N., Zhou L., Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O., Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D., Mansfield J.W., Collmer A., Buell R.
J. Bacteriol. 187:6488-6498(2005) [PubMed: 16159782] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000058 Genomic DNA. Translation: AAZ34804.1.
RefSeqYP_273341.1. NC_005773.3.

3D structure databases

ProteinModelPortalQ48MN1.
SMRQ48MN1. Positions 16-179.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ48MN1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3557366.
GenomeReviewsGene locus PSPPH_1071 in contig CP000058_GR.
KEGGpsp:PSPPH_1071.
NMPDRfig|264730.3.peg.318.
PATRIC19971236. VBIPseSyr78478_1124.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMAGAFRESS.
PhylomeDBQ48MN1.
ProtClustDBPRK12606.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ48MN1_PSE14
AccessionPrimary (citable) accession number: Q48MN1
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)