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Q48MB7

- Q48MB7_PSE14

UniProt

Q48MB7 - Q48MB7_PSE14

Protein

Glucose-6-phosphate 1-dehydrogenase

Gene

zwf1

Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.UniRule annotation

    Catalytic activityi

    D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei49 – 491NADPUniRule annotation
    Binding sitei145 – 1451NADPUniRule annotation
    Binding sitei175 – 1751SubstrateUniRule annotation
    Binding sitei179 – 1791SubstrateUniRule annotation
    Binding sitei213 – 2131SubstrateUniRule annotation
    Binding sitei232 – 2321SubstrateUniRule annotation
    Active sitei237 – 2371Proton acceptorUniRule annotation
    Binding sitei337 – 3371SubstrateUniRule annotation
    Binding sitei342 – 3421SubstrateUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi92 – 932NADPUniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-HAMAP
    2. NADP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Glucose metabolismUniRule annotation

    Keywords - Ligandi

    NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciPSAV264730:GKDE-1190-MONOMER.
    UniPathwayiUPA00115; UER00408.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate 1-dehydrogenaseUniRule annotation (EC:1.1.1.49UniRule annotation)
    Short name:
    G6PDUniRule annotation
    Gene namesi
    Name:zwf1Imported
    Synonyms:zwfUniRule annotation
    Ordered Locus Names:PSPPH_1188Imported
    OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)Imported
    Taxonomic identifieri264730 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000551: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi264730.PSPPH_1188.

    Structurei

    3D structure databases

    ProteinModelPortaliQ48MB7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glucose-6-phosphate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0364.
    HOGENOMiHOG000046191.
    KOiK00036.
    OMAiDSIMEAW.
    OrthoDBiEOG61308Z.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00966. G6PD.
    InterProiIPR001282. G6P_DH.
    IPR022675. G6P_DH_C.
    IPR022674. G6P_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR23429. PTHR23429. 1 hit.
    PfamiPF02781. G6PD_C. 1 hit.
    PF00479. G6PD_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000110. G6PD. 1 hit.
    PRINTSiPR00079. G6PDHDRGNASE.
    TIGRFAMsiTIGR00871. zwf. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q48MB7-1 [UniParc]FASTAAdd to Basket

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    MPLITVEPCT FALFGALGDL AVRKLFPALY QLDRAGLLHE DTKILALARE    50
    PGDEQSHLAY IEKSMRRFIP EAELEPDNLG RFLARLSYLH VDFLKAEDYV 100
    ALAERVGTAE TLIAYFATPA SVYGAICENL ASVNLAERTR AVLEKPIGHD 150
    LASSRRVNDA VAQFFPENRV YRIDHYLGKD TVQNLIALRF ANSLFETQWN 200
    QNHISHVEIT VAEKVGIEGR WGYFDQAGQL RDMIQNHLLQ LLCLIAMDPP 250
    SDLSADSIRD EKVKVLKALA PFTPERLATQ VVRGQYTAGY SEGKAVPGYL 300
    EEENSNTQSD TETFVALRAD IRNWRWSGTP FYLRTGKRMP QKMSQIVIHF 350
    KEPPHYIFAP EQRLQISNRL IIRLQPDEGI SLQVMTKDQG LDKGMQLRSG 400
    PLQLNFSDTY RSARVPDAYE RLLLEVMRGN QNLFVRKDEI EYAWQWCDQL 450
    IAGWKKAGDA PKPYPAGTWG PMSSIALITR DGRSWYGDM 489
    Length:489
    Mass (Da):55,509
    Last modified:September 13, 2005 - v1
    Checksum:iC107E61C93470596
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000058 Genomic DNA. Translation: AAZ33960.1.
    RefSeqiYP_273455.1. NC_005773.3.

    Genome annotation databases

    EnsemblBacteriaiAAZ33960; AAZ33960; PSPPH_1188.
    GeneIDi3556500.
    KEGGipsp:PSPPH_1188.
    PATRICi19971478. VBIPseSyr78478_1246.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000058 Genomic DNA. Translation: AAZ33960.1 .
    RefSeqi YP_273455.1. NC_005773.3.

    3D structure databases

    ProteinModelPortali Q48MB7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 264730.PSPPH_1188.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAZ33960 ; AAZ33960 ; PSPPH_1188 .
    GeneIDi 3556500.
    KEGGi psp:PSPPH_1188.
    PATRICi 19971478. VBIPseSyr78478_1246.

    Phylogenomic databases

    eggNOGi COG0364.
    HOGENOMi HOG000046191.
    KOi K00036.
    OMAi DSIMEAW.
    OrthoDBi EOG61308Z.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00408 .
    BioCyci PSAV264730:GKDE-1190-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00966. G6PD.
    InterProi IPR001282. G6P_DH.
    IPR022675. G6P_DH_C.
    IPR022674. G6P_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR23429. PTHR23429. 1 hit.
    Pfami PF02781. G6PD_C. 1 hit.
    PF00479. G6PD_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000110. G6PD. 1 hit.
    PRINTSi PR00079. G6PDHDRGNASE.
    TIGRFAMsi TIGR00871. zwf. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1448A / Race 6Imported.

    Entry informationi

    Entry nameiQ48MB7_PSE14
    AccessioniPrimary (citable) accession number: Q48MB7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 13, 2005
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3