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Protein

Malonyl CoA-acyl carrier protein transacylase

Gene

fabD

Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931UniRule annotation
Active sitei202 – 2021UniRule annotation

GO - Molecular functioni

  1. [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-1643-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylaseUniRule annotation (EC:2.3.1.39UniRule annotation)
Gene namesi
Name:fabDImported
Ordered Locus Names:PSPPH_1640Imported
OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)Imported
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000551 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi264730.PSPPH_1640.

Structurei

3D structure databases

ProteinModelPortaliQ48L42.
SMRiQ48L42. Positions 5-307.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fabD family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0331.
HOGENOMiHOG000036503.
KOiK00645.
OMAiPVVTNVE.
OrthoDBiEOG6W19KW.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q48L42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASLAFVFP GQGSQSLGML AEQGAQHPLI LDTFEQASEA LDYDLWALTQ
60 70 80 90 100
SGPVELLNQT DKTQPAILTA SIALWHVWLA EGGAVPAFVA GHSLGEYSAL
110 120 130 140 150
VAAQSLSLAD AVKLVECRGQ LMQEAVPAGQ GGMAAILGLD DADVIAACAE
160 170 180 190 200
AAQGEVVSAV NFNSPGQVVI AGSAEAVKRA MELCKARGAK RALSLPVSVP
210 220 230 240 250
SHCELMRPAA ERFAEAVEAI EWQAPEIALV QNVSASAVSD LATLKRDLLE
260 270 280 290 300
QLYKPVRWVE SIQCLASRGA TQLVECGPGK VLAGLNKRCA EGVITYNLDT
310
PDAFAAARAA LA
Length:312
Mass (Da):32,517
Last modified:September 13, 2005 - v1
Checksum:i299FD1AC0F67FFF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ36028.1.
RefSeqiWP_011168138.1. NC_005773.3.
YP_273883.1. NC_005773.3.

Genome annotation databases

EnsemblBacteriaiAAZ36028; AAZ36028; PSPPH_1640.
KEGGipsp:PSPPH_1640.
PATRICi19972450. VBIPseSyr78478_1727.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ36028.1.
RefSeqiWP_011168138.1. NC_005773.3.
YP_273883.1. NC_005773.3.

3D structure databases

ProteinModelPortaliQ48L42.
SMRiQ48L42. Positions 5-307.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264730.PSPPH_1640.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ36028; AAZ36028; PSPPH_1640.
KEGGipsp:PSPPH_1640.
PATRICi19972450. VBIPseSyr78478_1727.

Phylogenomic databases

eggNOGiCOG0331.
HOGENOMiHOG000036503.
KOiK00645.
OMAiPVVTNVE.
OrthoDBiEOG6W19KW.

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-1643-MONOMER.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1448A / Race 6Imported.

Entry informationi

Entry nameiQ48L42_PSE14
AccessioniPrimary (citable) accession number: Q48L42
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: April 29, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.