Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q48KZ1

- TIG_PSE14

UniProt

Q48KZ1 - TIG_PSE14

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Trigger factor

Gene

tig

Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

GO - Molecular functioni

  1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. protein folding Source: UniProtKB-HAMAP
  4. protein transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Chaperone, Isomerase, Rotamase

Keywords - Biological processi

Cell cycle, Cell division

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-1700-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trigger factorUniRule annotation (EC:5.2.1.8UniRule annotation)
Short name:
TFUniRule annotation
Alternative name(s):
PPIaseUniRule annotation
Gene namesi
Name:tigUniRule annotation
Ordered Locus Names:PSPPH_1697
OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000551: Chromosome

Subcellular locationi

Cytoplasm
Note: About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 436436Trigger factorPRO_0000256594Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264730.PSPPH_1697.

Structurei

3D structure databases

ProteinModelPortaliQ48KZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini161 – 24686PPIase FKBP-typeUniRule annotationAdd
BLAST

Domaini

Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.UniRule annotation

Sequence similaritiesi

Belongs to the FKBP-type PPIase family. Tig subfamily.UniRule annotation
Contains 1 PPIase FKBP-type domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0544.
HOGENOMiHOG000218239.
KOiK03545.
OMAiMQVSVEN.
OrthoDBiEOG63VBX3.

Family and domain databases

Gene3Di1.10.3120.10. 1 hit.
3.30.70.1050. 1 hit.
HAMAPiMF_00303. Trigger_factor_Tig.
InterProiIPR001179. PPIase_FKBP_dom.
IPR005215. Trig_fac.
IPR008880. Trigger_fac_C.
IPR008881. Trigger_fac_ribosome-bd_bac.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view]
PfamiPF00254. FKBP_C. 1 hit.
PF05698. Trigger_C. 1 hit.
PF05697. Trigger_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003095. Trigger_factor. 1 hit.
SUPFAMiSSF102735. SSF102735. 1 hit.
SSF109998. SSF109998. 1 hit.
TIGRFAMsiTIGR00115. tig. 1 hit.
PROSITEiPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q48KZ1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQVSVENTSA LERRMTIGVP AERIETEVNK RLQQTARKAK IPGFRPGKVP
60 70 80 90 100
MSVIRQRYED GARQEALGDL IQATFYEAVV EQKLNPAGAP AVEPKSFEKG
110 120 130 140 150
KDLEYVATFE VFPEFTVAGF DTIAVERLSA DVVDSDLDNM LEVLRKQNVR
160 170 180 190 200
FEVADRAAQN EDQLNIDFVG KVDGEVFAGG SATATQLVLG SGRMIPGFED
210 220 230 240 250
GLVGAKAGEE RVLNVTFPED YQNLELAGKA AEFTVTVNTV SEPKLPELNE
260 270 280 290 300
EFFKQFGIKE TGIEGFRTEV RKNMERELRQ AIKSKVKNQV MDGLLAANPI
310 320 330 340 350
EVPKALLENE VNRLRVQAVQ QFGGNIKPDQ LPAELFEEQA KRRVELGLIV
360 370 380 390 400
AEVVKQFDLK PDDARVREMI QEMASAYQEP EQVVAWYYKN EQQMNEVRSV
410 420 430
VLEEQVVDTV LQKASVTDKS VSYEEAVKPV EAPKAD
Length:436
Mass (Da):48,684
Last modified:September 13, 2005 - v1
Checksum:i74BABA0B9C679196
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ35278.1.
RefSeqiYP_273934.1. NC_005773.3.

Genome annotation databases

EnsemblBacteriaiAAZ35278; AAZ35278; PSPPH_1697.
GeneIDi3557856.
KEGGipsp:PSPPH_1697.
PATRICi19972569. VBIPseSyr78478_1780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ35278.1 .
RefSeqi YP_273934.1. NC_005773.3.

3D structure databases

ProteinModelPortali Q48KZ1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264730.PSPPH_1697.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ35278 ; AAZ35278 ; PSPPH_1697 .
GeneIDi 3557856.
KEGGi psp:PSPPH_1697.
PATRICi 19972569. VBIPseSyr78478_1780.

Phylogenomic databases

eggNOGi COG0544.
HOGENOMi HOG000218239.
KOi K03545.
OMAi MQVSVEN.
OrthoDBi EOG63VBX3.

Enzyme and pathway databases

BioCyci PSAV264730:GKDE-1700-MONOMER.

Family and domain databases

Gene3Di 1.10.3120.10. 1 hit.
3.30.70.1050. 1 hit.
HAMAPi MF_00303. Trigger_factor_Tig.
InterProi IPR001179. PPIase_FKBP_dom.
IPR005215. Trig_fac.
IPR008880. Trigger_fac_C.
IPR008881. Trigger_fac_ribosome-bd_bac.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view ]
Pfami PF00254. FKBP_C. 1 hit.
PF05698. Trigger_C. 1 hit.
PF05697. Trigger_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF003095. Trigger_factor. 1 hit.
SUPFAMi SSF102735. SSF102735. 1 hit.
SSF109998. SSF109998. 1 hit.
TIGRFAMsi TIGR00115. tig. 1 hit.
PROSITEi PS50059. FKBP_PPIASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1448A / Race 6.

Entry informationi

Entry nameiTIG_PSE14
AccessioniPrimary (citable) accession number: Q48KZ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: September 13, 2005
Last modified: November 26, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3