ID   XYLA_PSE14              Reviewed;         438 AA.
AC   Q48J73;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 25.
DE   RecName: Full=Xylose isomerase;
DE            EC=5.3.1.5;
GN   Name=xylA; OrderedLocusNames=PSPPH_2356;
OS   Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=264730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16159782; DOI=10.1128/JB.187.18.6488-6498.2005;
RA   Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R.,
RA   Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA   Crabtree J., Creasy T., Davidsen T.M., Haft D.H., Zafar N., Zhou L.,
RA   Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O.,
RA   Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D.,
RA   Mansfield J.W., Collmer A., Buell R.;
RT   "Whole-genome sequence analysis of Pseudomonas syringae pv.
RT   phaseolicola 1448A reveals divergence among pathovars in genes
RT   involved in virulence and transposition.";
RL   J. Bacteriol. 187:6488-6498(2005).
CC   -!- CATALYTIC ACTIVITY: D-xylose = D-xylulose.
CC   -!- COFACTOR: Binds 2 magnesium ions per subunit (By similarity).
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the xylose isomerase family.
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DR   EMBL; CP000058; AAZ36203.1; -; Genomic_DNA.
DR   RefSeq; YP_274557.1; -.
DR   GeneID; 3558817; -.
DR   GenomeReviews; CP000058_GR; PSPPH_2356.
DR   KEGG; psp:PSPPH_2356; -.
DR   NMPDR; fig|264730.3.peg.2447; -.
DR   HOGENOM; Q48J73; -.
DR   OMA; Q48J73; QFLIEPK.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009045; F:xylose isomerase activity; IEA:HAMAP.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:HAMAP.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP.
DR   HAMAP; MF_00455; -; 1.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   InterPro; IPR012307; Xyl_isomerase-typ_TIM-brl.
DR   InterPro; IPR013452; Xylose_isom_bac.
DR   InterPro; IPR001998; Xylose_isomerase.
DR   InterPro; IPR018115; Xylose_isomerase_AS.
DR   Gene3D; G3DSA:3.20.20.150; Xyl_isomerase-like_TIM-brl; 1.
DR   Pfam; PF01261; AP_endonuc_2; 1.
DR   PRINTS; PR00688; XYLOSISMRASE.
DR   TIGRFAMs; TIGR02630; xylose_isom_A; 1.
DR   PROSITE; PS51415; XYLOSE_ISOMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Cytoplasm; Isomerase;
KW   Magnesium; Metal-binding; Pentose shunt; Xylose metabolism.
FT   CHAIN         1    438       Xylose isomerase.
FT                                /FTId=PRO_0000236967.
FT   ACT_SITE    100    100       By similarity.
FT   ACT_SITE    103    103       By similarity.
FT   METAL       231    231       Magnesium 1 (By similarity).
FT   METAL       267    267       Magnesium 1 (By similarity).
FT   METAL       267    267       Magnesium 2 (By similarity).
FT   METAL       270    270       Magnesium 2 (By similarity).
FT   METAL       295    295       Magnesium 1 (By similarity).
FT   METAL       306    306       Magnesium 2 (By similarity).
FT   METAL       308    308       Magnesium 2 (By similarity).
FT   METAL       338    338       Magnesium 1 (By similarity).
SQ   SEQUENCE   438 AA;  49396 MW;  FDADDF19F1C8CA04 CRC64;
     MPYFPAVDKV RYEGPDSDSP LAFRHYDADK LILGKPMREH LRMAACYWHT FVWPGADMFG
     VGTFKRPWQG SGDPLELAIG KAETAFEFFS KLGIDYYSFH DTDVAPEGSS LKEYRNNFAQ
     MIDQLERHQE QTGIKLLWGT ANCFSNPRFA AGAASNPDPE VFAYAATQVF SAMNATQRLK
     GANYVLWGGR EGYETLLNTD LRQEREQLGR FMRMVVEHKH KIGFKGDLLI EPKPQEPTKH
     QYDYDSATVF GFLQQYGLEK EIKVNIEANH ATLAGHSFHH EIATAVSLGI FGSIDANRGD
     PQNGWDTDQF PNSVEEMTLA TYEILKAGGF TNGGYNFDSK VRRQSLDEVD LFHGHVAAMD
     VLALALERAA AMVQNDKLQQ FKDQRYAGWQ QPFGKSLLAG EFSLESLAKH AFDKDLNPQA
     VSGRQELLEG VVNRFIYF
//