ID   NUDC_PSE14              Reviewed;         278 AA.
AC   Q48IH8;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 25.
DE   RecName: Full=NADH pyrophosphatase;
DE            EC=3.6.1.22;
GN   Name=nudC; OrderedLocusNames=PSPPH_2609;
OS   Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=264730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16159782; DOI=10.1128/JB.187.18.6488-6498.2005;
RA   Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R.,
RA   Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA   Crabtree J., Creasy T., Davidsen T.M., Haft D.H., Zafar N., Zhou L.,
RA   Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O.,
RA   Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D.,
RA   Mansfield J.W., Collmer A., Buell R.;
RT   "Whole-genome sequence analysis of Pseudomonas syringae pv.
RT   phaseolicola 1448A reveals divergence among pathovars in genes
RT   involved in virulence and transposition.";
RL   J. Bacteriol. 187:6488-6498(2005).
CC   -!- CATALYTIC ACTIVITY: NAD(+) + H(2)O = AMP + NMN.
CC   -!- COFACTOR: Divalent ions. Manganese or magnesium (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. NudC subfamily.
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DR   EMBL; CP000058; AAZ35769.1; -; Genomic_DNA.
DR   RefSeq; YP_274803.1; -.
DR   GeneID; 3558368; -.
DR   GenomeReviews; CP000058_GR; PSPPH_2609.
DR   KEGG; psp:PSPPH_2609; -.
DR   NMPDR; fig|264730.3.peg.2595; -.
DR   HOGENOM; Q48IH8; -.
DR   OMA; Q48IH8; TWAREHR.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR   GO; GO:0000210; F:NAD+ diphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_00297; -; 1.
DR   InterPro; IPR015375; NADH_PPase-like_N.
DR   InterPro; IPR000086; NUDIX_hydrolase_core.
DR   InterPro; IPR015376; Znr_NADH_PPase.
DR   Gene3D; G3DSA:3.90.79.10; NUDIX_hydrolase; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   Pfam; PF09296; NUDIX-like; 1.
DR   Pfam; PF09297; zf-NADH-PPase; 1.
DR   PROSITE; PS00893; NUDIX; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Magnesium; Manganese; NAD.
FT   CHAIN         1    278       NADH pyrophosphatase.
FT                                /FTId=PRO_0000232118.
FT   MOTIF       175    196       Nudix box.
SQ   SEQUENCE   278 AA;  31068 MW;  5D2D23DE5202D67F CRC64;
     MAHPERWTTA VLDVEADGGL AVVQSDQGFL LDTNGAMFPR GWLAGLDLPV QSEHGIGYFE
     GEPVYLLVLE RSVAVEGCSW QGLRQFMLEG DFAVFQMLGY AAQVSTWARE HRFCGACGRA
     TVQIRGERAM FCEHDNLRLY PRISPSMIVL VTRGDEILLA RSPRFVTGMY SALAGFVEPG
     ESAEDCVHRE VMEEVQVRIK NLKYMGSQCW PFPHSMMLGF HAEYDSGDIV PQAEEIEDAR
     WFHIDDLPPL PANRSIARYL IEAYLAERSG APEPVLPG
//