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Q48HY9 (ARNT_PSE14) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
EC=2.4.2.43
Alternative name(s):
4-amino-4-deoxy-L-arabinose lipid A transferase
Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase
Undecaprenyl phosphate-alpha-L-Ara4N transferase
Gene names
Name:arnT
Ordered Locus Names:PSPPH_2806
OrganismPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) [Complete proteome] [HAMAP]
Taxonomic identifier264730 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length533 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides By similarity. HAMAP-Rule MF_01165

Catalytic activity

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate. HAMAP-Rule MF_01165

Pathway

Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis. HAMAP-Rule MF_01165

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01165.

Sequence similarities

Belongs to the glycosyltransferase 83 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 533533Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase HAMAP-Rule MF_01165
PRO_0000380014

Regions

Transmembrane10 – 3021Helical; Potential
Transmembrane64 – 8421Helical; Potential
Transmembrane86 – 10621Helical; Potential
Transmembrane113 – 13321Helical; Potential
Transmembrane137 – 15721Helical; Potential
Transmembrane170 – 19021Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane257 – 27721Helical; Potential
Transmembrane290 – 31021Helical; Potential
Transmembrane312 – 33221Helical; Potential
Transmembrane345 – 36521Helical; Potential
Transmembrane377 – 39721Helical; Potential
Transmembrane402 – 42221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q48HY9 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: EC6AD44E5DB647E8

FASTA53359,930
        10         20         30         40         50         60 
MHSRYRDGAL LLAAFLLAYL LPLGFHGLWI PDETRYAQIS QEMLHSGNWI APHFMGLRYF 

        70         80         90        100        110        120 
EKPPAGYWLI ALGQAVFGEN LFGVRIASAI STGLSVLLAY LLAGKIWSDP RKSFASALLF 

       130        140        150        160        170        180 
MSFGFVAGQA GYSNLDPQFT LWTNLTLVAF WYAVHSIDRA RLVAWTVVGV ACGMGFMTKG 

       190        200        210        220        230        240 
FLAWALPAII TLPYMLWQRR LTELLRFGPL AVVIAIAVCL PWALAVHQQE PDYWRYFFWH 

       250        260        270        280        290        300 
EHIRRFAGDN AQHAQPWWFY LPLLIAACLP WALLLPVTFK QAWQRKSRPD TAFLLLWLVL 

       310        320        330        340        350        360 
PLAFLSLSKG KLPTYILPCL LPLALLMADA LVEHLNQGRG RALRVNGIVN AALTFLGLLA 

       370        380        390        400        410        420 
LIYVQLKQPV YENEPMHLLL AVIVLTGWTL TNALQGIRPL TFWALPAVGS WLLIVLLPAA 

       430        440        450        460        470        480 
LPNDVVYNKT PDQFVARHQA ELAACTHLLS NDLGAASALS WRLKRPDITL FNTWGELEYG 

       490        500        510        520        530 
LGYPDVQGRQ VRLQGIDAWV TKARSEGRVG VIMRGKSDEE LRELELLPKD GQR

« Hide

References

[1]"Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition."
Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Crabtree J., Creasy T., Davidsen T.M., Haft D.H. expand/collapse author list , Zafar N., Zhou L., Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O., Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D., Mansfield J.W., Collmer A., Buell R.
J. Bacteriol. 187:6488-6498(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1448A / Race 6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000058 Genomic DNA. Translation: AAZ36871.1.
RefSeqYP_274993.1. NC_005773.3.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING264730.PSPPH_2806.

Protein family/group databases

CAZyGT83. Glycosyltransferase Family 83.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ36871; AAZ36871; PSPPH_2806.
GeneID3559501.
KEGGpsp:PSPPH_2806.
PATRIC19974937. VBIPseSyr78478_2951.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1807.
HOGENOMHOG000273002.
KOK07264.
OMAVACLPWS.
ProtClustDBPRK13279.

Enzyme and pathway databases

BioCycPSAV264730:GKDE-2809-MONOMER.
UniPathwayUPA00037.

Family and domain databases

HAMAPMF_01165. ArnT_transfer.
InterProIPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view]
PfamPF02366. PMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARNT_PSE14
AccessionPrimary (citable) accession number: Q48HY9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 13, 2005
Last modified: May 29, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents