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Q48HY9

- ARNT_PSE14

UniProt

Q48HY9 - ARNT_PSE14

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Protein

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase

Gene

arnT

Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotation

Catalytic activityi

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. mannosyltransferase activity Source: InterPro
  2. transferase activity, transferring pentosyl groups Source: InterPro

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-HAMAP
  2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
  3. protein O-linked glycosylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-2809-MONOMER.
UniPathwayiUPA00037.

Protein family/group databases

CAZyiGT83. Glycosyltransferase Family 83.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferaseUniRule annotation (EC:2.4.2.43UniRule annotation)
Alternative name(s):
4-amino-4-deoxy-L-arabinose lipid A transferaseUniRule annotation
Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation
Undecaprenyl phosphate-alpha-L-Ara4N transferaseUniRule annotation
Gene namesi
Name:arnTUniRule annotation
Ordered Locus Names:PSPPH_2806
OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000551: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei10 – 3021HelicalUniRule annotationAdd
BLAST
Transmembranei64 – 8421HelicalUniRule annotationAdd
BLAST
Transmembranei86 – 10621HelicalUniRule annotationAdd
BLAST
Transmembranei113 – 13321HelicalUniRule annotationAdd
BLAST
Transmembranei137 – 15721HelicalUniRule annotationAdd
BLAST
Transmembranei170 – 19021HelicalUniRule annotationAdd
BLAST
Transmembranei207 – 22721HelicalUniRule annotationAdd
BLAST
Transmembranei257 – 27721HelicalUniRule annotationAdd
BLAST
Transmembranei290 – 31021HelicalUniRule annotationAdd
BLAST
Transmembranei312 – 33221HelicalUniRule annotationAdd
BLAST
Transmembranei345 – 36521HelicalUniRule annotationAdd
BLAST
Transmembranei377 – 39721HelicalUniRule annotationAdd
BLAST
Transmembranei402 – 42221HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 533533Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferasePRO_0000380014Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264730.PSPPH_2806.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 83 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1807.
HOGENOMiHOG000273002.
KOiK07264.
OMAiGNWIAPH.
OrthoDBiEOG6NKQWN.

Family and domain databases

HAMAPiMF_01165. ArnT_transfer.
InterProiIPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view]
PfamiPF02366. PMT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q48HY9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHSRYRDGAL LLAAFLLAYL LPLGFHGLWI PDETRYAQIS QEMLHSGNWI
60 70 80 90 100
APHFMGLRYF EKPPAGYWLI ALGQAVFGEN LFGVRIASAI STGLSVLLAY
110 120 130 140 150
LLAGKIWSDP RKSFASALLF MSFGFVAGQA GYSNLDPQFT LWTNLTLVAF
160 170 180 190 200
WYAVHSIDRA RLVAWTVVGV ACGMGFMTKG FLAWALPAII TLPYMLWQRR
210 220 230 240 250
LTELLRFGPL AVVIAIAVCL PWALAVHQQE PDYWRYFFWH EHIRRFAGDN
260 270 280 290 300
AQHAQPWWFY LPLLIAACLP WALLLPVTFK QAWQRKSRPD TAFLLLWLVL
310 320 330 340 350
PLAFLSLSKG KLPTYILPCL LPLALLMADA LVEHLNQGRG RALRVNGIVN
360 370 380 390 400
AALTFLGLLA LIYVQLKQPV YENEPMHLLL AVIVLTGWTL TNALQGIRPL
410 420 430 440 450
TFWALPAVGS WLLIVLLPAA LPNDVVYNKT PDQFVARHQA ELAACTHLLS
460 470 480 490 500
NDLGAASALS WRLKRPDITL FNTWGELEYG LGYPDVQGRQ VRLQGIDAWV
510 520 530
TKARSEGRVG VIMRGKSDEE LRELELLPKD GQR
Length:533
Mass (Da):59,930
Last modified:September 13, 2005 - v1
Checksum:iEC6AD44E5DB647E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ36871.1.
RefSeqiYP_274993.1. NC_005773.3.

Genome annotation databases

EnsemblBacteriaiAAZ36871; AAZ36871; PSPPH_2806.
GeneIDi3559501.
KEGGipsp:PSPPH_2806.
PATRICi19974937. VBIPseSyr78478_2951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ36871.1 .
RefSeqi YP_274993.1. NC_005773.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264730.PSPPH_2806.

Protein family/group databases

CAZyi GT83. Glycosyltransferase Family 83.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ36871 ; AAZ36871 ; PSPPH_2806 .
GeneIDi 3559501.
KEGGi psp:PSPPH_2806.
PATRICi 19974937. VBIPseSyr78478_2951.

Phylogenomic databases

eggNOGi COG1807.
HOGENOMi HOG000273002.
KOi K07264.
OMAi GNWIAPH.
OrthoDBi EOG6NKQWN.

Enzyme and pathway databases

UniPathwayi UPA00037 .
BioCyci PSAV264730:GKDE-2809-MONOMER.

Family and domain databases

HAMAPi MF_01165. ArnT_transfer.
InterProi IPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view ]
Pfami PF02366. PMT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1448A / Race 6.

Entry informationi

Entry nameiARNT_PSE14
AccessioniPrimary (citable) accession number: Q48HY9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 13, 2005
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3