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Q48HY9

- ARNT_PSE14

UniProt

Q48HY9 - ARNT_PSE14

Protein

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase

Gene

arnT

Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotation

    Catalytic activityi

    4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. mannosyltransferase activity Source: InterPro
    2. transferase activity, transferring pentosyl groups Source: InterPro

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-HAMAP
    2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
    3. protein O-linked glycosylation Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciPSAV264730:GKDE-2809-MONOMER.
    UniPathwayiUPA00037.

    Protein family/group databases

    CAZyiGT83. Glycosyltransferase Family 83.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferaseUniRule annotation (EC:2.4.2.43UniRule annotation)
    Alternative name(s):
    4-amino-4-deoxy-L-arabinose lipid A transferaseUniRule annotation
    Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation
    Undecaprenyl phosphate-alpha-L-Ara4N transferaseUniRule annotation
    Gene namesi
    Name:arnTUniRule annotation
    Ordered Locus Names:PSPPH_2806
    OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
    Taxonomic identifieri264730 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000551: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 533533Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferasePRO_0000380014Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi264730.PSPPH_2806.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei10 – 3021HelicalUniRule annotationAdd
    BLAST
    Transmembranei64 – 8421HelicalUniRule annotationAdd
    BLAST
    Transmembranei86 – 10621HelicalUniRule annotationAdd
    BLAST
    Transmembranei113 – 13321HelicalUniRule annotationAdd
    BLAST
    Transmembranei137 – 15721HelicalUniRule annotationAdd
    BLAST
    Transmembranei170 – 19021HelicalUniRule annotationAdd
    BLAST
    Transmembranei207 – 22721HelicalUniRule annotationAdd
    BLAST
    Transmembranei257 – 27721HelicalUniRule annotationAdd
    BLAST
    Transmembranei290 – 31021HelicalUniRule annotationAdd
    BLAST
    Transmembranei312 – 33221HelicalUniRule annotationAdd
    BLAST
    Transmembranei345 – 36521HelicalUniRule annotationAdd
    BLAST
    Transmembranei377 – 39721HelicalUniRule annotationAdd
    BLAST
    Transmembranei402 – 42221HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 83 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1807.
    HOGENOMiHOG000273002.
    KOiK07264.
    OMAiGNWIAPH.
    OrthoDBiEOG6NKQWN.

    Family and domain databases

    HAMAPiMF_01165. ArnT_transfer.
    InterProiIPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view]
    PfamiPF02366. PMT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q48HY9-1 [UniParc]FASTAAdd to Basket

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    MHSRYRDGAL LLAAFLLAYL LPLGFHGLWI PDETRYAQIS QEMLHSGNWI    50
    APHFMGLRYF EKPPAGYWLI ALGQAVFGEN LFGVRIASAI STGLSVLLAY 100
    LLAGKIWSDP RKSFASALLF MSFGFVAGQA GYSNLDPQFT LWTNLTLVAF 150
    WYAVHSIDRA RLVAWTVVGV ACGMGFMTKG FLAWALPAII TLPYMLWQRR 200
    LTELLRFGPL AVVIAIAVCL PWALAVHQQE PDYWRYFFWH EHIRRFAGDN 250
    AQHAQPWWFY LPLLIAACLP WALLLPVTFK QAWQRKSRPD TAFLLLWLVL 300
    PLAFLSLSKG KLPTYILPCL LPLALLMADA LVEHLNQGRG RALRVNGIVN 350
    AALTFLGLLA LIYVQLKQPV YENEPMHLLL AVIVLTGWTL TNALQGIRPL 400
    TFWALPAVGS WLLIVLLPAA LPNDVVYNKT PDQFVARHQA ELAACTHLLS 450
    NDLGAASALS WRLKRPDITL FNTWGELEYG LGYPDVQGRQ VRLQGIDAWV 500
    TKARSEGRVG VIMRGKSDEE LRELELLPKD GQR 533
    Length:533
    Mass (Da):59,930
    Last modified:September 13, 2005 - v1
    Checksum:iEC6AD44E5DB647E8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000058 Genomic DNA. Translation: AAZ36871.1.
    RefSeqiWP_011168797.1. NC_005773.3.
    YP_274993.1. NC_005773.3.

    Genome annotation databases

    EnsemblBacteriaiAAZ36871; AAZ36871; PSPPH_2806.
    GeneIDi3559501.
    KEGGipsp:PSPPH_2806.
    PATRICi19974937. VBIPseSyr78478_2951.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000058 Genomic DNA. Translation: AAZ36871.1 .
    RefSeqi WP_011168797.1. NC_005773.3.
    YP_274993.1. NC_005773.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 264730.PSPPH_2806.

    Protein family/group databases

    CAZyi GT83. Glycosyltransferase Family 83.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAZ36871 ; AAZ36871 ; PSPPH_2806 .
    GeneIDi 3559501.
    KEGGi psp:PSPPH_2806.
    PATRICi 19974937. VBIPseSyr78478_2951.

    Phylogenomic databases

    eggNOGi COG1807.
    HOGENOMi HOG000273002.
    KOi K07264.
    OMAi GNWIAPH.
    OrthoDBi EOG6NKQWN.

    Enzyme and pathway databases

    UniPathwayi UPA00037 .
    BioCyci PSAV264730:GKDE-2809-MONOMER.

    Family and domain databases

    HAMAPi MF_01165. ArnT_transfer.
    InterProi IPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view ]
    Pfami PF02366. PMT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1448A / Race 6.

    Entry informationi

    Entry nameiARNT_PSE14
    AccessioniPrimary (citable) accession number: Q48HY9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3