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Protein

Inositol 2-dehydrogenase

Gene

iolG

Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) (Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).UniRule annotation

Catalytic activityi

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-3191-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol 2-dehydrogenaseUniRule annotation (EC:1.1.1.18UniRule annotation)
Alternative name(s):
Myo-inositol 2-dehydrogenaseUniRule annotation
Short name:
MI 2-dehydrogenaseUniRule annotation
Gene namesi
Name:iolGUniRule annotation
Ordered Locus Names:PSPPH_3188
OrganismiPseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) (Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6))
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000551 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336Inositol 2-dehydrogenasePRO_0000352581Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi264730.PSPPH_3188.

Structurei

3D structure databases

ProteinModelPortaliQ48GY3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRI. Bacteria.
COG0673. LUCA.
HOGENOMiHOG000227439.
KOiK00010.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG. 1 hit.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

Q48GY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKLGVIGT GAIGQDHIRR CSKTLVGSQV VAVTDINLEQ AAKVVRELDI
60 70 80 90 100
GAEVYADGHA LIAAPDVEAV LVCSWGPSHE EYVLAAIAAG KPVFCEKPLA
110 120 130 140 150
VTAEGCRHIV EAEIASGRRL VQVGFMRPYD QGYRALKSVI DSGRIGEPLM
160 170 180 190 200
LHCAHRNPRV GENYKTDMAI TDTLIHELNV LRWLLNDDYV SVQVVFPRKT
210 220 230 240 250
SKALAHMKDP QIVMLETARG TRIDVEVFVN CQYGYDIQCE VVGESGIAKL
260 270 280 290 300
PEPSQVQLRS EAKLSNAILM DWKDRFIAAY DVELQDFIDG VNAGTIYGPS
310 320 330
AWDGYAAAVA ADACVQAQNS GAVVPIALEM RPAFYD
Length:336
Mass (Da):36,554
Last modified:October 14, 2008 - v2
Checksum:i05F3A723614BE70C
GO

Sequence cautioni

The sequence AAZ36345 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ36345.1. Different initiation.
RefSeqiWP_002554084.1. NC_005773.3.

Genome annotation databases

EnsemblBacteriaiAAZ36345; AAZ36345; PSPPH_3188.
KEGGipsp:PSPPH_3188.
PATRICi19975762. VBIPseSyr78478_3353.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000058 Genomic DNA. Translation: AAZ36345.1. Different initiation.
RefSeqiWP_002554084.1. NC_005773.3.

3D structure databases

ProteinModelPortaliQ48GY3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264730.PSPPH_3188.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ36345; AAZ36345; PSPPH_3188.
KEGGipsp:PSPPH_3188.
PATRICi19975762. VBIPseSyr78478_3353.

Phylogenomic databases

eggNOGiENOG4105DRI. Bacteria.
COG0673. LUCA.
HOGENOMiHOG000227439.
KOiK00010.

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-3191-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG. 1 hit.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIOLG_PSE14
AccessioniPrimary (citable) accession number: Q48GY3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: October 14, 2008
Last modified: September 7, 2016
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.