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Q48FI4

- PUR5_PSE14

UniProt

Q48FI4 - PUR5_PSE14

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene
purM, PSPPH_3710
Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-3713-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:PSPPH_3710
OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000551: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 352352Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotationPRO_0000258385Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264730.PSPPH_3710.

Structurei

3D structure databases

ProteinModelPortaliQ48FI4.
SMRiQ48FI4. Positions 6-337.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q48FI4-1 [UniParc]FASTAAdd to Basket

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MSKQPSLSYK DAGVDIDAGE ALVERIKSVA KRTKRPEVMG GLGGFGALCE    50
IPAGYKQPVL VSGTDGVGTK LRLALNLNKH DTIGIDLVAM CVNDLVVCGA 100
EPLFFLDYYA TGKLNVDTAA QVVTGIGAGC ELAGCSLVGG ETAEMPGMYE 150
GEDYDLAGFC VGVVEKAEII DGSKVAAGDA LLALPSSGPH SNGYSLIRKI 200
IEVAGADIES IQLDGKPLTE LLMAPTRIYV KPLLKLIKET GAVKAMAHIT 250
GGGLLDNIPR VLPEGAQAVV DVASWQRPAV FDWLQQQGNV AENEMHRVLN 300
CGVGMVICVA QEHVEAALKV LREAGEQPWV IGQIATAAEG AAQVELKNLK 350
AH 352
Length:352
Mass (Da):36,925
Last modified:September 13, 2005 - v1
Checksum:i21C8E8CC0E4B376E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000058 Genomic DNA. Translation: AAZ35802.1.
RefSeqiYP_275852.1. NC_005773.3.

Genome annotation databases

EnsemblBacteriaiAAZ35802; AAZ35802; PSPPH_3710.
GeneIDi3558402.
KEGGipsp:PSPPH_3710.
PATRICi19976851. VBIPseSyr78478_3889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000058 Genomic DNA. Translation: AAZ35802.1 .
RefSeqi YP_275852.1. NC_005773.3.

3D structure databases

ProteinModelPortali Q48FI4.
SMRi Q48FI4. Positions 6-337.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264730.PSPPH_3710.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ35802 ; AAZ35802 ; PSPPH_3710 .
GeneIDi 3558402.
KEGGi psp:PSPPH_3710.
PATRICi 19976851. VBIPseSyr78478_3889.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci PSAV264730:GKDE-3713-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1448A / Race 6.

Entry informationi

Entry nameiPUR5_PSE14
AccessioniPrimary (citable) accession number: Q48FI4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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