Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q48DN1

- SYL_PSE14

UniProt

Q48DN1 - SYL_PSE14

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei630 – 6301ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSAV264730:GKDE-4398-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:PSPPH_4394
OrganismiPseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)
Taxonomic identifieri264730 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000551: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 868868Leucine--tRNA ligasePRO_1000009396Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264730.PSPPH_4394.

Structurei

3D structure databases

ProteinModelPortaliQ48DN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 5211"HIGH" regionAdd
BLAST
Motifi627 – 6315"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q48DN1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHELYQPREI EAAAQTFWDE QKSFEVSEQP GKDTFYCLSM FPYPSGKLHM
60 70 80 90 100
GHVRNYTIGD VISRYQRMLG KNVLQPLGWD AFGMPAENAA IDNNVAPAKW
110 120 130 140 150
TYENIAYMKN QLKSLGLAVD WSREVTTCKP DYYRWEQWLF TRLFEKGVIY
160 170 180 190 200
RKNGTVNWDP VDQTVLANEQ VIDGRGWRSG ALIEKREIPM YYFKITAYAD
210 220 230 240 250
ELLESLDELP GWPEQVKTMQ RNWIGRSRGM EVQFPYDQAS IGEAGALKVF
260 270 280 290 300
TTRPDTLMGA TYVAVAAEHP LATLAAQGNP GLQAFIDECK GGSVAEADVA
310 320 330 340 350
TQEKKGQPTS LFVEHPLTGE KLPVWVANYV LMHYGDGAVM AVPAHDERDF
360 370 380 390 400
EFATHYGLPI KPVVRTSAGD QTPAPWQPAY GEHGELINSG EFTGLNFQAA
410 420 430 440 450
FDAIEAALVK KSLGQSRTQF RLRDWGISRQ RYWGCPIPIV HCDTCGDVPV
460 470 480 490 500
PEDQLPVVLP EDVVPDGAGS PLARMPEFYE CSCPKCGAPA KRETDTMDTF
510 520 530 540 550
VESSWYYARY ASPHYEGGLV EPNAANHWLP VDQYIGGIEH AILHLLYARF
560 570 580 590 600
FHKLMRDEGL VTSNEPFKNL LTQGMVNAET YFRMETSGKK TWINPADVTL
610 620 630 640 650
ERDAKAKVIS AKLTSDGLPV EIGGTEKMSK SKKNGIDPQT MIDQYGADTC
660 670 680 690 700
RLFMMFASPP DMSLEWSDSG VEGSHRFLRR VWRLAQAHVA QGASTGLDIA
710 720 730 740 750
ALTDDQKTIR RSIHQAIRQA SQDIGQNQKF NTAVAQVMTL MNVLEKAPQV
760 770 780 790 800
TPQDRALLQE GLETVTLLLA PITPHISHEL WTQLGHNEPV IDAGWPAFDA
810 820 830 840 850
NALVQDSLQL VIQVNGKLRG HIEMPASASR EEVEAAARIN ENVLRFTDGL
860
TIRKVIVVPG KLVNIVAS
Length:868
Mass (Da):96,868
Last modified:September 13, 2005 - v1
Checksum:i6A74904B9092EE52
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000058 Genomic DNA. Translation: AAZ36139.1.
RefSeqiYP_276510.1. NC_005773.3.

Genome annotation databases

EnsemblBacteriaiAAZ36139; AAZ36139; PSPPH_4394.
GeneIDi3558749.
KEGGipsp:PSPPH_4394.
PATRICi19978277. VBIPseSyr78478_4595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000058 Genomic DNA. Translation: AAZ36139.1 .
RefSeqi YP_276510.1. NC_005773.3.

3D structure databases

ProteinModelPortali Q48DN1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264730.PSPPH_4394.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ36139 ; AAZ36139 ; PSPPH_4394 .
GeneIDi 3558749.
KEGGi psp:PSPPH_4394.
PATRICi 19978277. VBIPseSyr78478_4595.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci PSAV264730:GKDE-4398-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1448A / Race 6.

Entry informationi

Entry nameiSYL_PSE14
AccessioniPrimary (citable) accession number: Q48DN1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: October 29, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3