Reviewed, UniProtKB/Swiss-Prot Q48D01 (ADD_PSE14)

Names and origin

Protein names

Recommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase

Gene names

Name:	add
Ordered Locus Names:	PSPPH_4636

Organism

Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) [Complete proteome] [HAMAP]

Taxonomic identifier

264730 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 317	317	Adenosine deaminase HAMAP MF_00540		PRO_1000017676
Sites
	Active site	194	1	Potential
	Active site	242	1	Potential
	Active site	275	1	Potential
	Active site	276	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q48D01-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 114431C180569304	FASTA	317	36,102
	10 20 30 40 50 60 MYDWLNALPK AELHLHLEGS LEPELLFALA ERNKIALPWN DVETLRKAYA FNNLQEFLDL 70 80 90 100 110 120 YYRGADALRT EQDFYDLTWA YLLRCKEQNV IHTEPFFDPQ THTDRGIPFE VVLAGITGAL 130 140 150 160 170 180 KDGKSKLGVD SGLILSFLRH LSQEEAEKTL DQALPFRDAF VAVGLDSSEM GHPPSKFQRV 190 200 210 220 230 240 FDRARSEGFL TVAHAGEEGP PEYIWEALDL LKIQRIDHGV RAIEDERLMQ RIIDEQIPLT 250 260 270 280 290 300 VCPLSNTKLC VFDDMAQHNI LDMLERGVKV TVNSDDPAYF GGYVTENFHA LYTHLGMTED 310 QAKRLAQNSL DARLVKP

References

[1]

"Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition." Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Crabtree J., Creasy T., Davidsen T.M., Haft D.H. , Zafar N., Zhou L., Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O., Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D., Mansfield J.W., Collmer A., Buell R. J. Bacteriol. 187:6488-6498(2005) [PubMed: 16159782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000058 Genomic DNA. Translation: AAZ35126.1.
RefSeq	YP_276741.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3557701.
GenomeReviews	Gene locus PSPPH_4636 in contig CP000058_GR.
KEGG	psp:PSPPH_4636.
NMPDR	fig|264730.3.peg.4920.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q48D01.
OMA	Q48D01. LAQNSLD.
Family and domain databases
HAMAP	MF_00540. [Tree]
InterPro	IPR006650. A/AMP_deam_AS. IPR001365. A/AMP_deaminase. IPR006330. A_deaminase. [Graphical view]
PANTHER	PTHR11409. A/AMP_deaminase. 1 hit.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. aden_deam. 1 hit.
PROSITE	PS00485. A_DEAMINASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADD_PSE14

Accession

Primary (citable) accession number: Q48D01

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)