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Q489P3

- ASSY_COLP3

UniProt

Q489P3 - ASSY_COLP3

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Protein
Argininosuccinate synthase
Gene
argG, CPS_0463
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei42 – 421ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei94 – 941Citrulline By similarity
Binding sitei99 – 991Citrulline By similarity
Binding sitei124 – 1241ATP; via amide nitrogen By similarity
Binding sitei126 – 1261Aspartate By similarity
Binding sitei130 – 1301Aspartate By similarity
Binding sitei130 – 1301Citrulline By similarity
Binding sitei131 – 1311Aspartate By similarity
Binding sitei134 – 1341Citrulline By similarity
Binding sitei183 – 1831Citrulline By similarity
Binding sitei192 – 1921Citrulline By similarity
Binding sitei273 – 2731Citrulline By similarity
Binding sitei285 – 2851Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi14 – 229ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPSY167879:GI48-463-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:CPS_0463
OrganismiColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Taxonomic identifieri167879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia
ProteomesiUP000000547: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 418418Argininosuccinate synthaseUniRule annotation
PRO_0000263915Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi167879.CPS_0463.

Structurei

3D structure databases

ProteinModelPortaliQ489P3.
SMRiQ489P3. Positions 10-410.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiPWNEPTK.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q489P3-1 [UniParc]FASTAAdd to Basket

« Hide

MALAKKTIKK VVLAYSGGLD TSAIIPWLKE NYDGCEVIAF CADVGQGDEE    50
LEGVKEKAIA SGASECYVVD LKEEYVKEYI YPILKTGSVY EGQYLLGTSM 100
ARPIIAKAHI EVALKVGADA VCHGCTGKGN DQVRFESCFA ALAPELTVIA 150
PWREWDMVSR EDLLDYLAER NIPCAASLTK IYSRDANAWH ISHEGGELED 200
PWCEPSKEVW TMTVDPMDAP DVPEKVQLSF KEGELVGIDG KDFSQHGAGA 250
YEALMYLNEK GSAHGVGRID IVENRLVGMK SRGCYETPGG TILMAAYKGL 300
ETLILDKESL KYRESVGLEF SHVIYDGRWF TPLAKAQLAS AASFAEKLTG 350
DVVVKLYKGM AQVIQRRSPN SLYSEAFATF GADDVYDQKH AEGFIRLFSL 400
SSRITALSQK DSLKDKAE 418
Length:418
Mass (Da):45,950
Last modified:September 13, 2005 - v1
Checksum:iBC6740EAA891B1E8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ24202.1.
RefSeqiWP_011041324.1. NC_003910.7.
YP_267221.1. NC_003910.7.

Genome annotation databases

EnsemblBacteriaiAAZ24202; AAZ24202; CPS_0463.
GeneIDi3519550.
KEGGicps:CPS_0463.
PATRICi21464279. VBIColPsy94388_0404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ24202.1 .
RefSeqi WP_011041324.1. NC_003910.7.
YP_267221.1. NC_003910.7.

3D structure databases

ProteinModelPortali Q489P3.
SMRi Q489P3. Positions 10-410.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167879.CPS_0463.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ24202 ; AAZ24202 ; CPS_0463 .
GeneIDi 3519550.
KEGGi cps:CPS_0463.
PATRICi 21464279. VBIColPsy94388_0404.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi PWNEPTK.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci CPSY167879:GI48-463-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 34H / ATCC BAA-681.

Entry informationi

Entry nameiASSY_COLP3
AccessioniPrimary (citable) accession number: Q489P3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2005
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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