Q489N4 (AROK_COLP3) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 38.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Shikimate kinase Short name=SK EC=2.7.1.71 | ||||
| Gene names |
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| Organism | Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 167879 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia |
Protein attributes
| Sequence length | 172 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP MF_00109 |
| Catalytic activity | ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP MF_00109 |
| Cofactor | Binds 1 magnesium ion per subunit By similarity. HAMAP MF_00109 |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP MF_00109 |
| Subunit structure | Monomer By similarity. HAMAP MF_00109 |
| Subcellular location | Cytoplasm Probable HAMAP MF_00109. |
| Sequence similarities | Belongs to the shikimate kinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Magnesium Metal-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW shikimate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 172 | 172 | Shikimate kinase HAMAP MF_00109 | PRO_0000237866 | |||||
Regions | |||||||||
| Nucleotide binding | 14 – 19 | 6 | ATP By similarity | ||||||
Sites | |||||||||
| Metal binding | 18 | 1 | Magnesium By similarity | ||||||
| Binding site | 36 | 1 | Substrate By similarity | ||||||
| Binding site | 60 | 1 | Substrate By similarity | ||||||
| Binding site | 82 | 1 | Substrate; via amide nitrogen By similarity | ||||||
| Binding site | 120 | 1 | ATP By similarity | ||||||
| Binding site | 140 | 1 | Substrate By similarity | ||||||
| Binding site | 157 | 1 | ATP By similarity | ||||||
Sequences
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References
| [1] | "The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. Fraser C.M.Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 34H / ATCC BAA-681. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000083 Genomic DNA. Translation: AAZ26032.1. |
| RefSeq | YP_267230.1. NC_003910.7. |
3D structure databases | |
| ProteinModelPortal | Q489N4. |
| SMR | Q489N4. Positions 3-171. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q489N4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3520280. |
| GenomeReviews | Gene locus CPS_0472 in contig CP000083_GR. |
| KEGG | cps:CPS_0472. |
| NMPDR | fig|167879.3.peg.608. |
| PATRIC | 21464297. VBIColPsy94388_0413. |
| TIGR | CPS_0472. |
Phylogenomic databases | |
| eggNOG | COG0703. |
| HOGENOM | HBG335815. |
| OMA | VIYLRAN. |
Enzyme and pathway databases | |
| BioCyc | CPSY167879:CPS_0472-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00109. Shikimate_kinase. [Tree] |
| InterPro | IPR000623. Shikimate_kinase. IPR023000. Shikimate_kinase_CS. [Graphical view] |
| KO | K00891. |
| Pfam | PF01202. SKI. 1 hit. [Graphical view] |
| PRINTS | PR01100. SHIKIMTKNASE. |
| PROSITE | PS01128. SHIKIMATE_KINASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AROK_COLP3 | ||||||||
| Accession | Primary (citable) accession number: Q489N4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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