Q488Q3 (RLMG_COLP3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174

Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG

Gene names

Name:	rlmG
Ordered Locus Names:	CPS_0711

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859
Subcellular location	Cytoplasm Potential HAMAP MF_01859.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 392	392	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366450

Sequences

	Sequence		Length	Mass (Da)
	Q488Q3 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: FF0676AF11BDDE03	FASTA	392	43,756
	10 20 30 40 50 60 MISPFIVNDK NLFLSRFPVS QVNRSLQAWD SADEYLINHV HDQNLINAQT KVAIFNDAFG 70 80 90 100 110 120 ALAVNFCQST SENPEVISIN DSYISSEGAS YNIEQNSLDD SHFTQLNSLD SLPNNIDVIL 130 140 150 160 170 180 YKIPKSKSLL IEQLIQIKKS VNENCIFIAA DRAKEIHSST LKVFEKHLGT TKTSLAVKKA 190 200 210 220 230 240 RLVFCQFDNK QVHQSPFPTV WSIPHKSTND LPSRELTISN HANVYAREKL DIGARYFIEN 250 260 270 280 290 300 LPTVAANSTV IDLGCGNGVI GLTVLANQPE AHVQFIDEST MAISSAKQNI MTNLPDVIEQ 310 320 330 340 350 360 CEFTLNDSLT DIEGGSVDLI LCNPPFHQNT ATTDHIAWQM FKDSHRVLKK GGELRIIGNQ 370 380 390 KLAYHIKLQR LFGNETLIAS NDKFVTQSAI KR

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000083 Genomic DNA. Translation: AAZ28509.1.
RefSeq	YP_267461.1. NC_003910.7.
3D structure databases
ProteinModelPortal	Q488Q3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q488Q3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3522769.
GenomeReviews	Gene locus CPS_0711 in contig CP000083_GR.
KEGG	cps:CPS_0711.
NMPDR	fig|167879.3.peg.468.
PATRIC	21464741. VBIColPsy94388_0628.
TIGR	CPS_0711.
Phylogenomic databases
eggNOG	COG2813.
HOGENOM	HBG321931.
OMA	NRHLGYH.
Enzyme and pathway databases
BioCyc	CPSY167879:CPS_0711-MONOMER.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_COLP3

Accession

Primary (citable) accession number: Q488Q3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program