Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q48898 (Q48898_MYCAT) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismMycoplasma arthritidis EMBL AAC43976.1
Taxonomic identifier2111 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

Ontologies

Keywords
   DomainSignal EMBL AAC43976.1
   Technical term3D-structure PDB 2OJE PDB 1R5I PDB 2ICW PDB 3KPH
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential EMBL AAC43976.1
Chain26 – 238213superantigen EMBL AAC43976.1
PRO_5000144721

Regions

Region37 – 393Phosphate 1 binding PDB 2OJE PDB 1R5I
Region154 – 1574Phosphate 3 binding
Region197 – 2004Phosphate 5 binding

Sites

Binding site911Phosphate 3
Binding site1381Phosphate 1 PDB 1R5I
Binding site1421Phosphate 1 PDB 2OJE PDB 1R5I
Binding site2301Phosphate 6

Sequences

Sequence LengthMass (Da)Tools
Q48898 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 2A005A6263385243

FASTA23827,872
        10         20         30         40         50         60 
MKTKKLLIAT VTLATGLLGI LPLTSMKLRV ENPKKAQKHF VQNLNNVVFT NKELEDIYNL 

        70         80         90        100        110        120 
SNKEETKEVL KLFKLKVNQF YRHAFGIVND YNGLLEYKEI FNMMFLKLSV VFDTQRKEAN 

       130        140        150        160        170        180 
NVEQIKRNIA ILDEIMAKAD NDLSYFISQN KNFQELWDKA VKLTKEMKIK LKGQKLDLRD 

       190        200        210        220        230 
GEVAINKVRE LFGSDKNVKE LWWFRSLLVK GVYLIKRYYE GDIELKTTSD FAKAVFED 

« Hide

References

[1]"The sequence of the Mycoplasma arthritidis superantigen, MAM: identification of functional domains and comparison with microbial superantigens and plant lectin mitogens."
Cole B.C., Knudtson K.L., Oliphant A., Sawitzke A.D., Pole A., Manohar M., Benson L.S., Ahmed E., Atkin C.L.
J. Exp. Med. 183:1105-1110(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: PG-6 EMBL AAC43976.1.
[2]"Crystal structure of Mycoplasma arthritidis mitogen complexed with HLA-DR1 reveals a novel superantigen fold and a dimerized superantigen-MHC complex."
Zhao Y., Li Z., Drozd S.J., Guo Y., Mourad W., Li H.
Structure 12:277-288(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 26-238 IN COMPLEX WITH PHOSPHATE.
[3]"Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen."
Li H., Zhao Y., Guo Y., Li Z., Eisele L., Mourad W.
J. Biol. Chem. 282:5991-6000(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 25-238 IN COMPLEX WITH PHOSPHATE.
[4]"Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC."
Wang L., Zhao Y., Li Z., Guo Y., Jones L.L., Kranz D.M., Mourad W., Li H.
Nat. Struct. Mol. Biol. 14:169-171(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) OF 26-238.
[5]"Crystal structure of the Mycoplasma arthritidis-derived mitogen in apo form reveals a 3D domain-swapped dimer."
Liu L., Li Z., Guo Y., VanVranken S.J., Mourad W., Li H.
J. Mol. Biol. 399:367-376(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 26-237 IN COMPLEX WITH PHOSPHATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U33151 Genomic DNA. Translation: AAC43976.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1R5IX-ray2.60D/H26-238[»]
2ICWX-ray2.41G/H26-238[»]
2OJEX-ray3.00D/H25-238[»]
3KPHX-ray2.80A/B26-237[»]
ProteinModelPortalQ48898.
SMRQ48898. Positions 25-238.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.530. 1 hit.
1.20.120.390. 1 hit.
InterProIPR015326. M_arthritidis-der_mitogen.
IPR013997. M_arthritidis-der_mitogen_C.
IPR014022. M_arthritidis-der_mitogen_N.
[Graphical view]
PfamPF09245. MA-Mit. 1 hit.
[Graphical view]
SUPFAMSSF101344. SSF101344. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ48898.

Entry information

Entry nameQ48898_MYCAT
AccessionPrimary (citable) accession number: Q48898
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 22, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)