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Q48846

- BGAL_LACSK

UniProt

Q48846 - BGAL_LACSK

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Protein
Beta-galactosidase large subunit
Gene
lacL
Organism
Lactobacillus sakei
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei465 – 4651Proton donor By similarity
Active sitei533 – 5331Nucleophile By similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase large subunit (EC:3.2.1.23)
Short name:
Beta-gal large subunit
Alternative name(s):
Lactase large subunit
Gene namesi
Name:lacL
OrganismiLactobacillus sakei
Taxonomic identifieri1599 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 625625Beta-galactosidase large subunit
PRO_0000057670Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large and a small subunit.

Structurei

3D structure databases

ProteinModelPortaliQ48846.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SUPFAMiSSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q48846-1 [UniParc]FASTAAdd to Basket

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MQPNIQWLDT PAVFRVGQLP AHSDHRYYAT LAEMAQQQSS FEQSLNGTWQ    50
FHYSVNAASR PKSFYELAFD AQDFEPITVP QHIELAGYEQ LHYINTMYPW 100
EGHYYRRPAF STSDDKQHLG MFSEADYNPV GSYLHHFDLT PALRNQRVII 150
RFEGVEQAMY VWLNGQFIGY AEDSFTPSEF DLTPYLKETD NCLAVEVHKR 200
SSAAFIEDQD FFRFFGIFRD VKLLAKPRTH LEDLWVIPEY DVVQQTGQVK 250
LRLQFSGDEN RVHLRIRDQH QIILTADLTS GAQVNDLYKM PELVQAWSNQ 300
TPNLYTLELE VVDQAGETIE ISQQPFGFRK IEIKDKVMLL NGKRLVINGV 350
NRHEWHPETG RTITAEDEAW DIACMQRNHI NAVRTSHYPD RLSFYNGCDQ 400
AGIYMMAETN LESHGSWQKM GAVEPSWNVP GSYDEWEAAT LDRARTNFET 450
FKNHVSILFW SLGNESYAGS VLEKMNAYYK QQDPTRLVHY EGVFRAPEYK 500
ATISDVESRM YATPAEIKAY LDNAPQKPFI LCEYMHDMGN SLGGMQSYID 550
LLSQYDMYQG GFIWDFIDQA LLVTDPVTGQ RELRYGGDFD DRPSDYEFSG 600
DGLVFATRDE KPAMQEVRYY YGEHK 625
Length:625
Mass (Da):72,457
Last modified:November 1, 1996 - v1
Checksum:iC658A3C46136B886
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X82287 Genomic DNA. Translation: CAA57730.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X82287 Genomic DNA. Translation: CAA57730.1 .

3D structure databases

ProteinModelPortali Q48846.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
3.20.20.80. 1 hit.
InterProi IPR008979. Galactose-bd-like.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view ]
PRINTSi PR00132. GLHYDRLASE2.
SUPFAMi SSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Two genes encoding the beta-galactosidase of Lactobacillus sake."
    Obst M., Meding E.R., Vogel R.F., Hammes W.P.
    Microbiology 141:3059-3066(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DSM 20017.

Entry informationi

Entry nameiBGAL_LACSK
AccessioniPrimary (citable) accession number: Q48846
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: October 16, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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