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Q48806

- DLPA_LEGPH

UniProt

Q48806 - DLPA_LEGPH

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Protein
Protein DlpA
Gene
dlpA, lpg2683
Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. magnesium ion binding Source: InterPro
  3. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    BioCyciLPNE272624:GHDI-2682-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein DlpA
    Gene namesi
    Name:dlpA
    Ordered Locus Names:lpg2683
    OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
    Taxonomic identifieri272624 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
    ProteomesiUP000000609: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 615615Protein DlpA
    PRO_0000083821Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272624.lpg2683.

    Structurei

    3D structure databases

    ProteinModelPortaliQ48806.

    Family & Domainsi

    Sequence similaritiesi

    To M.jannaschii MJ0644 in the C-terminal section.

    Phylogenomic databases

    eggNOGiCOG0684.
    HOGENOMiHOG000278037.
    OMAiCIIRENS.
    OrthoDBiEOG64BQ2K.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    3.50.30.40. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR024084. IsoPropMal-DH-like_dom.
    IPR005493. RNase_E_inh/diMeMenaQ_MeTrfase.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    PF03737. Methyltransf_6. 1 hit.
    [Graphical view]
    SUPFAMiSSF89562. SSF89562. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q48806-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKSTDPIKIA VLPGDGIGIE VTEATLPVFE VLDVPVILNY GDIGWEFWKK    50
    EGAAIPSRTW QLIASSDTVL LGAITSKPQR EAKQELSNAL KKSNPYYVSP 100
    VIQLRQGLDL FANVRPCFSI DDQSKPFNFC IIRENSEGLY CGFDYFPLPK 150
    AIHSLLAESQ HWQTIPADEA SCALRLQSKS GLTRLFDFAF KHAMQTGMPR 200
    VTLADKPNVL RESGEFTRKI FESTAQRYPK IQADILNVDA VALWLIKSPE 250
    KFGVIVAENM FGDILSDVGA GVMGGLGLAP SANIGDKGSY FEPVHGSGPR 300
    IRKNCANPSA MFLTISMLLN HFGYPDRAKK IVNAVMQVIK EKRFITYDLG 350
    GHATTTDMAN AVIEHCARLN ASCLSKDFNP TPKENLIESD TMPNLLQQLI 400
    NCNSAEISDA LDACGIEGGL LSIKPLSQGM KIIGPAYTIQ YLPREKKGTA 450
    FHNAANYIDK VPKHSVIVID NNGQIDCTVW GDLLTHTALR NNIMGTVVHG 500
    AVRDVESIRS TNYPVFCTGI YMCSGKNRVY KANEQCPLSI NGVTINPGDI 550
    IFADDNGVLV IPNDRLQEVV NKTIAIRLTE ERIKTAIASG STLEQAREDY 600
    CYEQPWLGIN KKRES 615
    Length:615
    Mass (Da):67,705
    Last modified:November 1, 1996 - v1
    Checksum:i78387A390E7695E4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U07940 Genomic DNA. Translation: AAA79904.1.
    AE017354 Genomic DNA. Translation: AAU28741.1.
    PIRiS61390.
    RefSeqiWP_010948383.1. NC_020521.1.
    YP_007566889.1. NC_020521.1.
    YP_096688.1. NC_002942.5.

    Genome annotation databases

    EnsemblBacteriaiAAU28741; AAU28741; lpg2683.
    GeneIDi14799038.
    3079431.
    KEGGilpn:lpg2683.
    lpu:LPE509_00346.
    PATRICi22332725. VBILegPne29832_2864.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U07940 Genomic DNA. Translation: AAA79904.1 .
    AE017354 Genomic DNA. Translation: AAU28741.1 .
    PIRi S61390.
    RefSeqi WP_010948383.1. NC_020521.1.
    YP_007566889.1. NC_020521.1.
    YP_096688.1. NC_002942.5.

    3D structure databases

    ProteinModelPortali Q48806.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 272624.lpg2683.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU28741 ; AAU28741 ; lpg2683 .
    GeneIDi 14799038.
    3079431.
    KEGGi lpn:lpg2683.
    lpu:LPE509_00346.
    PATRICi 22332725. VBILegPne29832_2864.

    Phylogenomic databases

    eggNOGi COG0684.
    HOGENOMi HOG000278037.
    OMAi CIIRENS.
    OrthoDBi EOG64BQ2K.

    Enzyme and pathway databases

    BioCyci LPNE272624:GHDI-2682-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    3.50.30.40. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR024084. IsoPropMal-DH-like_dom.
    IPR005493. RNase_E_inh/diMeMenaQ_MeTrfase.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    PF03737. Methyltransf_6. 1 hit.
    [Graphical view ]
    SUPFAMi SSF89562. SSF89562. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene."
      Berger K.H., Merriam J.J., Isberg R.R.
      Mol. Microbiol. 14:809-822(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Philadelphia 1 / ATCC 33152 / DSM 7513.

    Entry informationi

    Entry nameiDLPA_LEGPH
    AccessioniPrimary (citable) accession number: Q48806
    Secondary accession number(s): Q5ZS36
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: September 3, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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