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Q48806 (DLPA_LEGPH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Protein DlpA
Gene names
Name:dlpA
Ordered Locus Names:lpg2683
OrganismLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) [Complete proteome] [HAMAP]
Taxonomic identifier272624 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella ›

Protein attributes

Sequence length615 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

To M.jannaschii MJ0644 in the C-terminal section.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 615615Protein DlpA
PRO_0000083821

Sequences

Sequence LengthMass (Da)Tools
Q48806 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 78387A390E7695E4

FASTA61567,705
        10         20         30         40         50         60 
MKSTDPIKIA VLPGDGIGIE VTEATLPVFE VLDVPVILNY GDIGWEFWKK EGAAIPSRTW 

        70         80         90        100        110        120 
QLIASSDTVL LGAITSKPQR EAKQELSNAL KKSNPYYVSP VIQLRQGLDL FANVRPCFSI 

       130        140        150        160        170        180 
DDQSKPFNFC IIRENSEGLY CGFDYFPLPK AIHSLLAESQ HWQTIPADEA SCALRLQSKS 

       190        200        210        220        230        240 
GLTRLFDFAF KHAMQTGMPR VTLADKPNVL RESGEFTRKI FESTAQRYPK IQADILNVDA 

       250        260        270        280        290        300 
VALWLIKSPE KFGVIVAENM FGDILSDVGA GVMGGLGLAP SANIGDKGSY FEPVHGSGPR 

       310        320        330        340        350        360 
IRKNCANPSA MFLTISMLLN HFGYPDRAKK IVNAVMQVIK EKRFITYDLG GHATTTDMAN 

       370        380        390        400        410        420 
AVIEHCARLN ASCLSKDFNP TPKENLIESD TMPNLLQQLI NCNSAEISDA LDACGIEGGL 

       430        440        450        460        470        480 
LSIKPLSQGM KIIGPAYTIQ YLPREKKGTA FHNAANYIDK VPKHSVIVID NNGQIDCTVW 

       490        500        510        520        530        540 
GDLLTHTALR NNIMGTVVHG AVRDVESIRS TNYPVFCTGI YMCSGKNRVY KANEQCPLSI 

       550        560        570        580        590        600 
NGVTINPGDI IFADDNGVLV IPNDRLQEVV NKTIAIRLTE ERIKTAIASG STLEQAREDY 

       610 
CYEQPWLGIN KKRES

« Hide

References

« Hide 'large scale' references
[1]"Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene."
Berger K.H., Merriam J.J., Isberg R.R.
Mol. Microbiol. 14:809-822(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The genomic sequence of the accidental pathogen Legionella pneumophila."
Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G., Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V., Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S. expand/collapse author list , Georghiou A., Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A., Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A., Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A., Russo J.J.
Science 305:1966-1968(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Philadelphia 1 / ATCC 33152 / DSM 7513.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U07940 Genomic DNA. Translation: AAA79904.1.
AE017354 Genomic DNA. Translation: AAU28741.1.
PIRS61390.
RefSeqYP_096688.1. NC_002942.5.

3D structure databases

ProteinModelPortalQ48806.
ModBaseSearch...

Protein-protein interaction databases

STRING272624.lpg2683.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU28741; AAU28741; lpg2683.
GeneID3079431.
KEGGlpn:lpg2683.
PATRIC22332725. VBILegPne29832_2864.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0684.
HOGENOMHOG000278037.
OMAMANAVIE.
ProtClustDBCLSK833555.

Enzyme and pathway databases

BioCycLPNE272624:GHDI-2693-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
3.50.30.40. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
IPR005493. RNase_E_inh/diMeMenaQ_MeTrfase.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
PF03737. Methyltransf_6. 1 hit.
[Graphical view]
SUPFAMSSF89562. RNaseE_inh/diMeMenaQ_MeTrfase. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDLPA_LEGPH
AccessionPrimary (citable) accession number: Q48806
Secondary accession number(s): Q5ZS36
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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