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Protein

Protein-arginine kinase

Gene

mcsB

Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the specific phosphorylation of arginine residues in proteins.UniRule annotation

Catalytic activityi

ATP + a [protein]-L-arginine = ADP + a [protein]-N(omega)-phospho-L-arginine.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei79 – 791ATPUniRule annotation
Binding sitei113 – 1131ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi24 – 285ATPUniRule annotation
Nucleotide bindingi164 – 1685ATPUniRule annotation
Nucleotide bindingi195 – 2006ATPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLMON169963:LMO0231-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-arginine kinaseUniRule annotation (EC:2.7.14.1UniRule annotation)
Gene namesi
Name:mcsBUniRule annotation
Ordered Locus Names:lmo0231
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000817 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 340340Protein-arginine kinasePRO_0000212026Add
BLAST

Proteomic databases

PaxDbiQ48759.

Interactioni

Protein-protein interaction databases

STRINGi169963.lmo0231.

Structurei

3D structure databases

ProteinModelPortaliQ48759.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 242222Phosphagen kinase C-terminalUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.UniRule annotation
Contains 1 phosphagen kinase C-terminal domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG41066A3. Bacteria.
COG3869. LUCA.
HOGENOMiHOG000082112.
KOiK19405.
OMAiIIMQERV.
OrthoDBiEOG6NKR1D.
PhylomeDBiQ48759.

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
HAMAPiMF_00602. Prot_Arg_kinase.
InterProiIPR023660. Arg_Kinase.
IPR000749. ATP-guanido_PTrfase.
IPR022414. ATP-guanido_PTrfase_cat.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PANTHERiPTHR11547. PTHR11547. 2 hits.
PfamiPF00217. ATP-gua_Ptrans. 1 hit.
[Graphical view]
PROSITEiPS51510. PHOSPHAGEN_KINASE_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q48759-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVFEPRLSS WLENAGDDDD VVLSSRIRLA RNLKDEQFPI YEQKEEIVDN
60 70 80 90 100
IAEVFDDNFI LIKMNQISLL QKALLVEKHL ISPYMMNKSE YGAVLLNEEE
110 120 130 140 150
NVSIMLNEED HLRIQCMTPG LRLFDALEAA LQIDGYVEEK LSYAFDKEFG
160 170 180 190 200
YLTSCVTNIG TGMRASVMVH LPGLVTTKRI KSVIEAIRSL GFVVRGIYGE
210 220 230 240 250
GSMPASNIFQ VSNQVTLGKT EAEIVEDLTQ VMEQIIMQER VARTTLKQKF
260 270 280 290 300
HIALEDRVFR SYGLLMNCRI ISMKEAADAI SDIRFGVELG FFEHISRQKM
310 320 330 340
NELVLFSQPA FLRREAGRDM DELEEKVIRA KVIREILGDK
Length:340
Mass (Da):38,855
Last modified:November 1, 1996 - v1
Checksum:i0932C1C357509E07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U40604 Genomic DNA. Translation: AAC44445.1.
AL591974 Genomic DNA. Translation: CAD00758.1.
PIRiAH1103.
RefSeqiNP_463762.1. NC_003210.1.
WP_010989379.1. NC_003210.1.

Genome annotation databases

EnsemblBacteriaiCAD00758; CAD00758; CAD00758.
GeneIDi987202.
KEGGilmo:lmo0231.
PATRICi20309506. VBILisMon69206_0239.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U40604 Genomic DNA. Translation: AAC44445.1.
AL591974 Genomic DNA. Translation: CAD00758.1.
PIRiAH1103.
RefSeqiNP_463762.1. NC_003210.1.
WP_010989379.1. NC_003210.1.

3D structure databases

ProteinModelPortaliQ48759.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi169963.lmo0231.

Proteomic databases

PaxDbiQ48759.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD00758; CAD00758; CAD00758.
GeneIDi987202.
KEGGilmo:lmo0231.
PATRICi20309506. VBILisMon69206_0239.

Phylogenomic databases

eggNOGiENOG41066A3. Bacteria.
COG3869. LUCA.
HOGENOMiHOG000082112.
KOiK19405.
OMAiIIMQERV.
OrthoDBiEOG6NKR1D.
PhylomeDBiQ48759.

Enzyme and pathway databases

BioCyciLMON169963:LMO0231-MONOMER.

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
HAMAPiMF_00602. Prot_Arg_kinase.
InterProiIPR023660. Arg_Kinase.
IPR000749. ATP-guanido_PTrfase.
IPR022414. ATP-guanido_PTrfase_cat.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PANTHERiPTHR11547. PTHR11547. 2 hits.
PfamiPF00217. ATP-gua_Ptrans. 1 hit.
[Graphical view]
PROSITEiPS51510. PHOSPHAGEN_KINASE_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes."
    Rouquette C., Ripio M.T., Pellegrini E., Bolla J.-M., Tascon R.I., Vazquez-Boland J.A., Berche P.
    Mol. Microbiol. 21:977-987(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LO28 / Serovar 1/2c.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-679 / EGD-e.

Entry informationi

Entry nameiMCSB_LISMO
AccessioniPrimary (citable) accession number: Q48759
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: November 1, 1996
Last modified: February 17, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.